{"title":"新型量子点增强肿瘤成像。","authors":"Ashwin Nair, Jinhui Shen, Paul Thevenot, Tong Cai, Zhibing Hu, Liping Tang","doi":"10.1109/NANO.2008.197","DOIUrl":null,"url":null,"abstract":"<p><p>So as to develop an effective tool for tumor imaging, we have embedded quantum dots (QD) in hydrogel nanoparticles. Their uptake in cancer cells has been studied in vitro and in a mice tumor model. Compared with QD alone, the QDs embedded in nanoparticles showed higher uptake in the tumor tissue. This novel conjugate can serve as a good imaging tool and also has the potential to serve as a carrier for drugs.</p>","PeriodicalId":89614,"journal":{"name":"Proceedings of the ... IEEE Conference on Nanotechnology. IEEE Conference on Nanotechnology","volume":"8 ","pages":"650-653"},"PeriodicalIF":0.0000,"publicationDate":"2008-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261784/pdf/nihms339294.pdf","citationCount":"0","resultStr":"{\"title\":\"Novel Quantum Dots for Enhanced Tumor Imaging.\",\"authors\":\"Ashwin Nair, Jinhui Shen, Paul Thevenot, Tong Cai, Zhibing Hu, Liping Tang\",\"doi\":\"10.1109/NANO.2008.197\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>So as to develop an effective tool for tumor imaging, we have embedded quantum dots (QD) in hydrogel nanoparticles. Their uptake in cancer cells has been studied in vitro and in a mice tumor model. Compared with QD alone, the QDs embedded in nanoparticles showed higher uptake in the tumor tissue. This novel conjugate can serve as a good imaging tool and also has the potential to serve as a carrier for drugs.</p>\",\"PeriodicalId\":89614,\"journal\":{\"name\":\"Proceedings of the ... IEEE Conference on Nanotechnology. IEEE Conference on Nanotechnology\",\"volume\":\"8 \",\"pages\":\"650-653\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-08-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261784/pdf/nihms339294.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the ... IEEE Conference on Nanotechnology. IEEE Conference on Nanotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/NANO.2008.197\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the ... IEEE Conference on Nanotechnology. IEEE Conference on Nanotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NANO.2008.197","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
So as to develop an effective tool for tumor imaging, we have embedded quantum dots (QD) in hydrogel nanoparticles. Their uptake in cancer cells has been studied in vitro and in a mice tumor model. Compared with QD alone, the QDs embedded in nanoparticles showed higher uptake in the tumor tissue. This novel conjugate can serve as a good imaging tool and also has the potential to serve as a carrier for drugs.