L Lagrone, S Cole, A Schondelmeyer, K Maleta, M J Manary
{"title":"当地生产的即食补充食品是在业务环境中治疗中度急性营养不良的有效方法。","authors":"L Lagrone, S Cole, A Schondelmeyer, K Maleta, M J Manary","doi":"10.1179/146532810X12703901870651","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Typical treatment of moderate acute malnutrition, simple wasting, in sub-Saharan Africa consists of dietary counselling and/or general or targeted distribution of corn/soy-blended flour (CSB). A randomised clinical effectiveness trial in 2007 showed CSB to be less effective than ready-to-use supplementary food (RUSF).</p><p><strong>Aim: </strong>To determine the operational effectiveness of treating moderate acute malnutrition with RUSF.</p><p><strong>Methods: </strong>Children aged 6-59 months were recruited in rural southern Malawi. Each child received 65 kcal/kg/d of locally produced soy/peanut RUSF, a product that provided about 1 RDA of each micronutrient. Anthropometric measurements were taken every 2 weeks and additional rations of RUSF were distributed at this time if the child remained wasted. Study participation lasted up to 8 weeks.</p><p><strong>Results: </strong>Of the 2417 children enrolled, 80% recovered, 4% defaulted, 0.4% died, 12% remained moderately wasted and 3% developed severe acute malnutrition. Weight, length and MUAC gain were 2.6 g/kg/d, 0.2 mm/d and 0.1 mm/d respectively. Cost per child treated was $5.39.</p><p><strong>Conclusions: </strong>This intervention proved to be robust, maintaining high recovery rates and low default rates when instituted without the additional supervision and beneficiary incentives of a research setting.</p>","PeriodicalId":50759,"journal":{"name":"Annals of Tropical Paediatrics","volume":"30 2","pages":"103-8"},"PeriodicalIF":0.0000,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1179/146532810X12703901870651","citationCount":"46","resultStr":"{\"title\":\"Locally produced ready-to-use supplementary food is an effective treatment of moderate acute malnutrition in an operational setting.\",\"authors\":\"L Lagrone, S Cole, A Schondelmeyer, K Maleta, M J Manary\",\"doi\":\"10.1179/146532810X12703901870651\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Typical treatment of moderate acute malnutrition, simple wasting, in sub-Saharan Africa consists of dietary counselling and/or general or targeted distribution of corn/soy-blended flour (CSB). A randomised clinical effectiveness trial in 2007 showed CSB to be less effective than ready-to-use supplementary food (RUSF).</p><p><strong>Aim: </strong>To determine the operational effectiveness of treating moderate acute malnutrition with RUSF.</p><p><strong>Methods: </strong>Children aged 6-59 months were recruited in rural southern Malawi. Each child received 65 kcal/kg/d of locally produced soy/peanut RUSF, a product that provided about 1 RDA of each micronutrient. Anthropometric measurements were taken every 2 weeks and additional rations of RUSF were distributed at this time if the child remained wasted. Study participation lasted up to 8 weeks.</p><p><strong>Results: </strong>Of the 2417 children enrolled, 80% recovered, 4% defaulted, 0.4% died, 12% remained moderately wasted and 3% developed severe acute malnutrition. Weight, length and MUAC gain were 2.6 g/kg/d, 0.2 mm/d and 0.1 mm/d respectively. Cost per child treated was $5.39.</p><p><strong>Conclusions: </strong>This intervention proved to be robust, maintaining high recovery rates and low default rates when instituted without the additional supervision and beneficiary incentives of a research setting.</p>\",\"PeriodicalId\":50759,\"journal\":{\"name\":\"Annals of Tropical Paediatrics\",\"volume\":\"30 2\",\"pages\":\"103-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1179/146532810X12703901870651\",\"citationCount\":\"46\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Tropical Paediatrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1179/146532810X12703901870651\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Tropical Paediatrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1179/146532810X12703901870651","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Locally produced ready-to-use supplementary food is an effective treatment of moderate acute malnutrition in an operational setting.
Background: Typical treatment of moderate acute malnutrition, simple wasting, in sub-Saharan Africa consists of dietary counselling and/or general or targeted distribution of corn/soy-blended flour (CSB). A randomised clinical effectiveness trial in 2007 showed CSB to be less effective than ready-to-use supplementary food (RUSF).
Aim: To determine the operational effectiveness of treating moderate acute malnutrition with RUSF.
Methods: Children aged 6-59 months were recruited in rural southern Malawi. Each child received 65 kcal/kg/d of locally produced soy/peanut RUSF, a product that provided about 1 RDA of each micronutrient. Anthropometric measurements were taken every 2 weeks and additional rations of RUSF were distributed at this time if the child remained wasted. Study participation lasted up to 8 weeks.
Results: Of the 2417 children enrolled, 80% recovered, 4% defaulted, 0.4% died, 12% remained moderately wasted and 3% developed severe acute malnutrition. Weight, length and MUAC gain were 2.6 g/kg/d, 0.2 mm/d and 0.1 mm/d respectively. Cost per child treated was $5.39.
Conclusions: This intervention proved to be robust, maintaining high recovery rates and low default rates when instituted without the additional supervision and beneficiary incentives of a research setting.