当地生产的即食补充食品是在业务环境中治疗中度急性营养不良的有效方法。

L Lagrone, S Cole, A Schondelmeyer, K Maleta, M J Manary
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引用次数: 46

摘要

背景:在撒哈拉以南非洲,对中度急性营养不良(单纯消瘦)的典型治疗包括饮食咨询和/或普遍或有针对性地分发玉米/大豆混合面粉(CSB)。2007年的一项随机临床有效性试验表明,CSB的效果不如即食辅食(RUSF)。目的:探讨RUSF治疗中度急性营养不良的操作效果。方法:在马拉维南部农村招募6-59个月的儿童。每个儿童每天摄入65千卡的当地生产的大豆/花生RUSF,该产品为每种微量营养素提供约1 RDA。每两周进行一次人体测量,如果儿童仍然消瘦,则在此时分发额外的RUSF。研究参与时间长达8周。结果:在入选的2417名儿童中,80%康复,4%违约,0.4%死亡,12%中度消瘦,3%发展为严重急性营养不良。体重2.6 g/kg/d,体长0.2 mm/d, MUAC增重0.1 mm/d。每个儿童的治疗费用为5.39美元。结论:这种干预被证明是强有力的,在没有额外监督和研究设置的受益人激励的情况下,维持了高回收率和低违约率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Locally produced ready-to-use supplementary food is an effective treatment of moderate acute malnutrition in an operational setting.

Background: Typical treatment of moderate acute malnutrition, simple wasting, in sub-Saharan Africa consists of dietary counselling and/or general or targeted distribution of corn/soy-blended flour (CSB). A randomised clinical effectiveness trial in 2007 showed CSB to be less effective than ready-to-use supplementary food (RUSF).

Aim: To determine the operational effectiveness of treating moderate acute malnutrition with RUSF.

Methods: Children aged 6-59 months were recruited in rural southern Malawi. Each child received 65 kcal/kg/d of locally produced soy/peanut RUSF, a product that provided about 1 RDA of each micronutrient. Anthropometric measurements were taken every 2 weeks and additional rations of RUSF were distributed at this time if the child remained wasted. Study participation lasted up to 8 weeks.

Results: Of the 2417 children enrolled, 80% recovered, 4% defaulted, 0.4% died, 12% remained moderately wasted and 3% developed severe acute malnutrition. Weight, length and MUAC gain were 2.6 g/kg/d, 0.2 mm/d and 0.1 mm/d respectively. Cost per child treated was $5.39.

Conclusions: This intervention proved to be robust, maintaining high recovery rates and low default rates when instituted without the additional supervision and beneficiary incentives of a research setting.

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Annals of Tropical Paediatrics
Annals of Tropical Paediatrics 医学-热带医学
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