脂肪组织的炎症成分作为代谢综合征治疗的靶点。

Forum of Nutrition Pub Date : 2009-01-01 Epub Date: 2009-04-07 DOI:10.1159/000212742
Rina Yu, Chu-Sook Kim, Ji-Hye Kang
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引用次数: 27

摘要

肥胖是胰岛素抵抗、2型糖尿病、心血管疾病等多种代谢性疾病病因学中的独立危险因素。在本章中,我们将讨论肥胖引起的炎症与肥胖相关代谢综合征的潜在联系,并讨论肥胖相关炎症成分(如免疫细胞、细胞因子/趋化因子和脂肪因子)如何引发肥胖相关病理。我们特别关注抗炎食物因子/植物化学物质可能有助于抑制肥胖引起的炎症和代谢综合征的发生和发展的假设。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inflammatory components of adipose tissue as target for treatment of metabolic syndrome.

Obesity is an independent risk factor in the etiology of various metabolic diseases such as insulin resistance, type 2 diabetes and cardiovascular diseases. In this chapter, we discuss obesity-induced inflammation as a potential link with obesity-related metabolic syndrome, and discuss how obesity-related inflammatory components such as immune cells, and cytokines/chemokines and adipocy-tokines, provoke obesity-related pathologies. In particular, we focus on the hypothesis that anti-inflammatory food factors/phytochemicals may be useful for inhibiting the initiation and development of obesity-induced inflammation and metabolic syndrome.

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