【原发性肾上腺非霍奇金淋巴瘤致肾上腺功能衰竭1例报告及文献复习】。

B Hernández Marín, V M Díaz Muñoz de la Espada, R Alvarez Alvarez, S Encinas García, P Khosravi Shahi, R Pérez Fernández, G Pérez Manga
{"title":"【原发性肾上腺非霍奇金淋巴瘤致肾上腺功能衰竭1例报告及文献复习】。","authors":"B Hernández Marín,&nbsp;V M Díaz Muñoz de la Espada,&nbsp;R Alvarez Alvarez,&nbsp;S Encinas García,&nbsp;P Khosravi Shahi,&nbsp;R Pérez Fernández,&nbsp;G Pérez Manga","doi":"10.4321/s0212-71992008000300007","DOIUrl":null,"url":null,"abstract":"<p><p>We report a case of 78-year old man who presented with symptoms of adrenal insufficiency. The computed tomography (CT) scan showed the presence of bilateral adrenal masses. A CT-scan guided needle biopsy revealed diffuse large- B cell lymphoma. The absence of pathological findings in clinical, bone marrow and CT scan examinations supported the diagnosis of primary non-Hodgkin Lymphoma of the adrenal glands. The patient was treated with four cycles of R-CHOP chemotherapy with Rituximab, liposomal Doxorubicin, Cyclophosphamide, Vincristine and Prednisolone. At the end of fourth cycle there was radiological improvement but the chemotherapy was stopped because of IV grade toxicity. He completed treatment with radiotherapy of right adrenal mass. Few days after finishing radiation therapy the patient died due to a disseminated infection. No progressive disease was founded.</p>","PeriodicalId":50798,"journal":{"name":"Anales De Medicina Interna","volume":"25 3","pages":"131-3"},"PeriodicalIF":0.0000,"publicationDate":"2008-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"[Adrenal failure caused by primary adrenal non-Hodgkin lymphoma: a case report and review of the literature].\",\"authors\":\"B Hernández Marín,&nbsp;V M Díaz Muñoz de la Espada,&nbsp;R Alvarez Alvarez,&nbsp;S Encinas García,&nbsp;P Khosravi Shahi,&nbsp;R Pérez Fernández,&nbsp;G Pérez Manga\",\"doi\":\"10.4321/s0212-71992008000300007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We report a case of 78-year old man who presented with symptoms of adrenal insufficiency. The computed tomography (CT) scan showed the presence of bilateral adrenal masses. A CT-scan guided needle biopsy revealed diffuse large- B cell lymphoma. The absence of pathological findings in clinical, bone marrow and CT scan examinations supported the diagnosis of primary non-Hodgkin Lymphoma of the adrenal glands. The patient was treated with four cycles of R-CHOP chemotherapy with Rituximab, liposomal Doxorubicin, Cyclophosphamide, Vincristine and Prednisolone. At the end of fourth cycle there was radiological improvement but the chemotherapy was stopped because of IV grade toxicity. He completed treatment with radiotherapy of right adrenal mass. Few days after finishing radiation therapy the patient died due to a disseminated infection. No progressive disease was founded.</p>\",\"PeriodicalId\":50798,\"journal\":{\"name\":\"Anales De Medicina Interna\",\"volume\":\"25 3\",\"pages\":\"131-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anales De Medicina Interna\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4321/s0212-71992008000300007\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anales De Medicina Interna","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4321/s0212-71992008000300007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

摘要

我们报告一例78岁的男子谁提出了肾上腺功能不全的症状。计算机断层扫描显示双侧肾上腺肿块。ct扫描引导下穿刺活检显示弥漫性大B细胞淋巴瘤。临床、骨髓及CT检查均无病理表现,支持原发性肾上腺非霍奇金淋巴瘤的诊断。患者接受利妥昔单抗、阿霉素脂质体、环磷酰胺、长春新碱和强的松龙4个周期的R-CHOP化疗。在第四个周期结束时,放射学有所改善,但由于IV级毒性而停止化疗。他完成了右肾上腺肿块的放疗治疗。放疗结束后几天,患者死于播散性感染。没有发现进行性疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Adrenal failure caused by primary adrenal non-Hodgkin lymphoma: a case report and review of the literature].

We report a case of 78-year old man who presented with symptoms of adrenal insufficiency. The computed tomography (CT) scan showed the presence of bilateral adrenal masses. A CT-scan guided needle biopsy revealed diffuse large- B cell lymphoma. The absence of pathological findings in clinical, bone marrow and CT scan examinations supported the diagnosis of primary non-Hodgkin Lymphoma of the adrenal glands. The patient was treated with four cycles of R-CHOP chemotherapy with Rituximab, liposomal Doxorubicin, Cyclophosphamide, Vincristine and Prednisolone. At the end of fourth cycle there was radiological improvement but the chemotherapy was stopped because of IV grade toxicity. He completed treatment with radiotherapy of right adrenal mass. Few days after finishing radiation therapy the patient died due to a disseminated infection. No progressive disease was founded.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信