[阿尔茨海默病语义入侵错误的原型价值]。

Marianne Canolle, Mouloud Messaoudi, Bronia Ayoub, Irène Descours, Patrick Bocquet, Marie-Christine Gely-Nargeot, Jacques Touchon
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引用次数: 9

摘要

语义入侵是在阿尔茨海默病患者中经常观察到的不适当反应。它们与需要记住的单词属于同一类别,但它们的原型价值在很大程度上仍未被探索。原型是某一特定词汇范畴中最具代表性的词。原型值是根据不同的标准来衡量的:书面和口头词汇的使用频率、使用频率、典型性程度、熟悉程度和引用等级。本研究的目的是评估17例轻度至重度痴呆阿尔茨海默病患者在Grober & Buschke程序(RL/RI 16项)提示回忆过程中产生的侵入的原型价值。将原型值与1)17名对照受试者和2)词汇数据库“lexque 3”提供的范畴规范进行比较。结果表明,入侵物品的原型价值显著高于目标物品。原型值随着疾病的进展而增加,并根据所使用的评价标准。因此,在“使用频率”、“典型程度”和“熟悉程度”的标准下,原型值随着痴呆的严重程度呈指数增长。相比之下,尽管病理发展,但当以“引用等级”和“词汇频率”(口头和书面)为标准评估时,原型价值有所下降。总之,对阿尔茨海默病侵入错误原型价值的定性分析开辟了新的临床和方法学思考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Prototypic value of semantic intrusion errors in Alzheimer's disease].

Semantic intrusions are inappropriate responses frequently observed in patients with Alzheimer's disease. They belong to the same category as the words to be remembered, but their prototypic value remains largely unexplored. The prototype is the most representative word in a particular lexical category. The prototypic value is measured according to different criteria: written and oral lexical frequency, frequency of use, degree of typicality, degree of familiarity and rank of quotation. The objective of the study was to evaluate the prototypic value of intrusions produced by 17 Alzheimer's patients with mild to severe dementia, during the cued recall of the Grober & Buschke procedure (RL/RI 16 items). The prototypic value was compared to the categorial norms provided by 1) 17 control subjects and 2) the lexical database "Lexique 3". The results show that intrusions had a significantly higher prototypic value than targeted items. The prototypic value increased with the progression of the disease, and according to the evaluation criteria used. Thus with the criteria "frequency of use", "degree of typicality" and "degree of familiarity," the prototypic value increased exponentially with the severity of dementia. In contrast, in spite of the development of the pathology, the prototypic value decreased when assessed by the criteria of "rank of quotation", and "lexical frequency" (oral and written). In conclusion, the qualitative analysis of the prototypic value of intrusion errors in Alzheimers opens up new clinical and methodological considerations.

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