酒精中毒长期死亡率:一项描述性分析。

Raymond M Costello
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引用次数: 11

摘要

目的:短期酒精中毒死亡率研究对长期综合治疗方案规划的影响有限。因此,这项研究进行了超过33年的研究,以回答诸如酗酒者如何,何时以及为什么在从综合社区治疗计划的中间护理部分出院后死亡等问题。方法:在1963年、1964年、1967年、1970年和1972年,将500名酗酒者分为五组,每组100人,在社区综合治疗方案的中间护理单位接受治疗,随访33-42年,记录死亡情况。计算病死率(CFR)和病因特异性死亡率,并与随访滞后和种族相关。结果:449名受试者在39年内死亡,其中50%的死亡发生在第11年。年平均CFR为0.057。死因特异性死亡率随时间和种族而异。由于生活方式原因(即自杀、他杀、事故和艾滋病)造成的死亡在随访的前几年不成比例地发生,最年轻和少数民族(黑人和西班牙裔)的死亡人数与白人不成比例。白人往往活得更长,但所有三个种族/民族都死于生活方式的原因,在年轻时,在随访系列的早期,在相对较老的年龄死于癌症和肺部疾病的随访系列的后期。结论:综合治疗方案必须在中级护理出院后尽快为生活方式危机做好准备,并在后期为器官疾病做好准备。种族是酗酒人群早期死亡的重要预测因素,在综合治疗方案规划中必须予以考虑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-term mortality from alcoholism: a descriptive analysis.

Objective: Short-term alcoholism mortality studies are limited in their ramifications for long-term, comprehensive treatment program planning. Therefore, this study was pursued for more than 33 years to answer questions such as how, when, and why alcoholics die after discharge from an intermediate care component of a comprehensive community-based treatment program.

Method: A cohort of 500 alcoholics admitted in five groups of 100 in the years 1963, 1964, 1967, 1970, and 1972 to an intermediate care unit of a community-based, comprehensive treatment program was tracked for 33-42 years to document deaths. Case-fatality rate (CFR) and cause-specific mortality rate were computed and correlated with follow-up lag and ethnicity.

Results: Four hundred and forty nine subjects died within 39 years, with 50% of the deaths occurring by Year 11. Average annual CFR was .057. Cause-specific mortality varied over time and with ethnicity. Deaths attributable to lifestyle causes (i.e., suicide, homicide, accidents, and AIDS) occurred disproportionately in the earlier years of the follow-up, claiming the youngest and ethnic minority (black and Hispanic) persons disproportionately to white. Whites tended to live longer, but all three racial/ethnic groups died of lifestyle causes at young ages, early in the follow-up series, and at relatively older ages from cancer and diseases of the lung late in the follow-up series.

Conclusions: Comprehensive treatment programs must prepare for lifestyle crises soon after discharge from intermediate care and for organ diseases later. Ethnicity is a significant predictor of early death in alcoholic cohorts and must be considered in comprehensive treatment program planning.

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