小世界网络理论在酒精流行病学中的应用。

Richard J Braun, Robert A Wilson, John A Pelesko, J Robert Buchanan, James P Gleeson
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引用次数: 18

摘要

目的:本研究建立了一个结构化人群(如社区和大学校园)酒精滥用的数学模型。该研究采用了一个网络模型,该模型除了个人相识之外,还能够纳入各种形式的连通性成员,例如地理邻近和共同的组织。该模型还包含了一个弹性维度,表明网络中每个个体对酒精滥用的易感性。该模型有能力模拟将酒精滥用者转移到非滥用者网络的影响,无论是作为治疗的结果还是作为自助组织的成员。方法:采用小世界模型。每个人的三次方程(图上的顶点)控制着一个人在0到1之间的酒精依赖状态的演变,其中1表示酒精依赖的绝对确定性。仿真结果依赖于初始条件、网络结构和网络弹性分布。这些模拟包含了社会网络的多种实现,显示了不同网络结构的影响。结果:该模型表明,酒精滥用的流行可以通过治疗相对较小比例的研究人群来最小化。在我们研究的小群体中,临界点是研究群体的10%或更少,但我们强调这是在这个模型的限制和假设范围内。结论:使用一个简单的模型,结合社会网络邻居在结构化人群中的影响,有望帮助告知治疗和预防政策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Applications of small-world network theory in alcohol epidemiology.

Objective: This study develops a mathematical model of alcohol abuse in structured populations, such as communities and college campuses. The study employs a network model that has the capacity to incorporate a variety of forms of connectivity membership besides personal acquaintance, such as geographic proximity and common organizations. The model also incorporates a resilience dimension that indicates the susceptibility of each individual in a network to alcohol abuse. The model has the capacity to simulate the effect of moving alcohol abusers into networks of nonabusers, either as the result of treatment or membership in self-help organizations.

Method: The study employs a small-world model. A cubic equation for each person (vertex on a graph) governs the evolution of an individual's state between 0 and 1 with regard to alcohol dependence, with 1 indicating absolute certainty of alcohol dependence. The simulations are dependent on initial conditions, the structure of the network, and the resilience distribution of the network. The simulations incorporate multiple realizations of social networks, showing the effect of different network structures.

Results: The model suggests that the prevalence of alcohol abuse can be minimized by treating a relatively small percentage of the study population. In the small populations that we studied, the critical point was 10% or less of the study population, but we emphasize that this is within the limitations and assumptions of this model.

Conclusions: The use of a simple model that incorporates the influence of the social network neighbors in structured populations shows promise for helping to inform treatment and prevention policy.

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