滋养细胞中HLA-G蛋白的表达。

Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA Pub Date : 2005-12-01

Yan-qiu Wang, Shi-ling Chen, Fu-qi Xing

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引用次数: 0

摘要

目的:探讨人白细胞抗原蛋白G (HLA-G)在不同滋养细胞和妊娠不同阶段的表达情况。方法:采用免疫组化方法(SP)检测不同妊娠期正常胎盘和滋养细胞中HLA-G蛋白的表达。结果:HLA-G蛋白的表达呈现时空变化，其表达位点位于胎盘外滋养层(EVT)，妊娠前、中期较高，妊娠晚期较低(p结论:HLA-G蛋白在妊娠不同阶段及不同滋养层的表达可能与滋养层侵袭受控制有关。

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[Expression of HLA-G protein in trophoblast cells].

Objective: To investigate the expression of human leucocyte antigen protein G (HLA-G) in different trophoblast cells and different stages of pregnancy.

Methods: The expression of HLA-G protein in normal placenta and trophoblasts of different trimesters was detected using immunohistochemical method (SP).

Results: HLA-G protein expression exhibited spatio-temporal changes, which located in the extravillous trophoblast (EVT) and was higher in the placenta of the first and second trimesters while lower in the third trimester (P<0.01).

Conclusion: HLA-G protein expression in different stages of pregnancy and different trophoblasts may be related to the controlled invasion of the trophoblast.

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Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA

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