Sophie Landre, Anne-Lise Bienvenu, Patrick Miailhes, Paul Abraham, Marie Simon, Agathe Becker, Anne Conrad, Guillaume Bonnot, Yobouet Ines Kouakou, Christian Chidiac, Gilles Leboucher, Thomas Rimmelé, Laurent Argaud, Stephane Picot
{"title":"高寄生虫血症复发,严重恶性疟原虫疟疾发作,用青蒿琥酯单药治疗。","authors":"Sophie Landre, Anne-Lise Bienvenu, Patrick Miailhes, Paul Abraham, Marie Simon, Agathe Becker, Anne Conrad, Guillaume Bonnot, Yobouet Ines Kouakou, Christian Chidiac, Gilles Leboucher, Thomas Rimmelé, Laurent Argaud, Stephane Picot","doi":"10.1016/j.ijid.2021.02.080","DOIUrl":null,"url":null,"abstract":"<p><p>A patient presenting with severe malaria, with hyperparasitaemia, received 7-day artesunate monotherapy. A severe recrudescence was detected and attributed to hyperparasitaemia, monotherapy and a polyclonal infection without Kelch 13 gene mutation. A second treatment with artesunate, then quinine, followed by artemether-lumefantrine, was successful.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"345-348"},"PeriodicalIF":0.0000,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.02.080","citationCount":"3","resultStr":"{\"title\":\"Recrudescence of a high parasitaemia, severe Plasmodium falciparum malaria episode, treated by artesunate monotherapy.\",\"authors\":\"Sophie Landre, Anne-Lise Bienvenu, Patrick Miailhes, Paul Abraham, Marie Simon, Agathe Becker, Anne Conrad, Guillaume Bonnot, Yobouet Ines Kouakou, Christian Chidiac, Gilles Leboucher, Thomas Rimmelé, Laurent Argaud, Stephane Picot\",\"doi\":\"10.1016/j.ijid.2021.02.080\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A patient presenting with severe malaria, with hyperparasitaemia, received 7-day artesunate monotherapy. A severe recrudescence was detected and attributed to hyperparasitaemia, monotherapy and a polyclonal infection without Kelch 13 gene mutation. A second treatment with artesunate, then quinine, followed by artemether-lumefantrine, was successful.</p>\",\"PeriodicalId\":505767,\"journal\":{\"name\":\"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases\",\"volume\":\" \",\"pages\":\"345-348\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.ijid.2021.02.080\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.ijid.2021.02.080\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/2/23 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.ijid.2021.02.080","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/2/23 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Recrudescence of a high parasitaemia, severe Plasmodium falciparum malaria episode, treated by artesunate monotherapy.
A patient presenting with severe malaria, with hyperparasitaemia, received 7-day artesunate monotherapy. A severe recrudescence was detected and attributed to hyperparasitaemia, monotherapy and a polyclonal infection without Kelch 13 gene mutation. A second treatment with artesunate, then quinine, followed by artemether-lumefantrine, was successful.