细胞和免疫疗法治疗HIV-1感染。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2021-02-24 DOI:10.24875/AIDSRev.20000110

Wei Li, Qiqiang Zhou, Lingbo Xia, Ruixiang Zou, Wei Zou

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引用次数: 0

摘要

艾滋病毒-1感染在全世界造成若干人死亡，仍然是一个全球健康问题。联合抗逆转录病毒疗法(cART)抑制病毒复制，防止CD4+ T细胞损失，从而减缓艾滋病毒疾病进展。然而，cART并不能根除HIV-1。感染者必须终生接受治疗，治疗中断将导致病毒反弹。

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Cellular and Immune Therapy for Treating HIV-1 Infection.

HIV-1 infection has caused a number of deaths worldwide and remains a global health concern. Combined antiretroviral therapy (cART) inhibits viral replication, prevents CD4+ T cell loss, and thus slows HIV disease progression. However, cART does not eradicate HIV-1. Infected individuals must remain on treatment for their entire lives and treatment interruption will result in viral rebound.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.