血管段阻抗响应随电极配置变化的有限元模拟

Q3 Biochemistry, Genetics and Molecular Biology
Journal of Electrical Bioimpedance Pub Date : 2020-12-31 eCollection Date: 2020-01-01 DOI:10.2478/joeb-2020-0017
M Amini, H Kalvøy, Ø G Martinsen
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引用次数: 0

摘要

将生物组织作为三维(3D)模型进行监测非常重要。测量技术和测量电极在提供精确的三维测量中发挥着重要作用。生物阻抗光谱法已被证明是一种无创方法,可以实时监测三维结构。另一方面,电极制造技术的进步使得使用不同配置的柔性电极成为可能,从而使三维测量成为可能。然而,设计用于监测三维结构的实验测量装置既费钱又费时,而且需要许多组织模型。有限元建模方法提供了一种简单的替代方法,可在开始实验测量前研究电极和测量装置的性能。因此,在本研究中,我们采用 COMSOL Multiphysics 有限元建模方法来模拟改变电极配置对静脉段阻抗光谱测量的影响。为此,我们对不同电极配置的模型进行了模拟。模拟结果为我们找到最佳电极配置提供了可能,包括电极的几何形状、数量和尺寸,这些都可以在以后的实验测量设置中使用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Finite Element Simulation of the Impedance Response of a Vascular Segment as a Function of Changes in Electrode Configuration.

Finite Element Simulation of the Impedance Response of a Vascular Segment as a Function of Changes in Electrode Configuration.

Finite Element Simulation of the Impedance Response of a Vascular Segment as a Function of Changes in Electrode Configuration.

Finite Element Simulation of the Impedance Response of a Vascular Segment as a Function of Changes in Electrode Configuration.

Monitoring a biological tissue as a three dimensional (3D) model is of high importance. Both the measurement technique and the measuring electrode play substantial roles in providing accurate 3D measurements. Bioimpedance spectroscopy has proven to be a noninvasive method providing the possibility of monitoring a 3D construct in a real time manner. On the other hand, advances in electrode fabrication has made it possible to use flexible electrodes with different configurations, which makes 3D measurements possible. However, designing an experimental measurement set-up for monitoring a 3D construct can be costly and time consuming and would require many tissue models. Finite element modeling methods provide a simple alternative for studying the performance of the electrode and the measurement set-up before starting with the experimental measurements. Therefore, in this study we employed the COMSOL Multiphysics finite element modeling method for simulating the effects of changing the electrode configuration on the impedance spectroscopy measurements of a venous segment. For this purpose, the simulations were performed for models with different electrode configurations. The simulation results provided us with the possibility of finding the optimal electrode configuration including the geometry, number and dimensions of the electrodes, which can be later employed in the experimental measurement set-up.

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来源期刊
Journal of Electrical Bioimpedance
Journal of Electrical Bioimpedance Engineering-Biomedical Engineering
CiteScore
3.00
自引率
0.00%
发文量
8
审稿时长
17 weeks
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