Paul D. Stein MD , Afzal Beemath MD , Ronald E. Olson PhD
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引用次数: 550
摘要
目的肥胖是否是肺栓塞或深静脉血栓形成的独立危险因素尚未完全确定。方法利用全国医院出院调查数据库，进一步调查静脉血栓栓塞性疾病患者肥胖的潜在风险。结果肥胖患者与非肥胖患者发生深静脉血栓的相对危险度为2.50(95%可信区间[CI] = 2.49 ~ 2.51)。肺栓塞的相对危险度为2.21 (95% CI = 2.20-2.23)。肥胖女性发生深静脉血栓的相对风险高于肥胖男性，分别为2.75 (95% CI = 2.74-2.76)和2.02 (95% CI = 2.01-2.04)。肥胖对40岁以下的男性和女性的影响最大。结论肥胖是男性和女性发生静脉血栓栓塞性疾病的危险因素。
Obesity as a risk factor in venous thromboembolism
Purpose
Whether obesity is an independent risk factor for pulmonary embolism or deep venous thrombosis has not been fully determined.
Methods
We used the database of the National Hospital Discharge Survey to further investigate the potential risk of obesity in venous thromboembolic disease.
Results
The relative risk of deep venous thrombosis, comparing obese patients with non-obese patients, was 2.50 (95% confidence interval [CI] = 2.49-2.51). The relative risk of pulmonary embolism was 2.21 (95% CI = 2.20-2.23). Obese females had a greater relative risk for deep venous thrombosis than obese males, 2.75 (95% CI = 2.74-2.76) versus 2.02 (95% CI = 2.01-2.04). Obesity had the greatest impact on both men and women aged less than 40 years.
Conclusion
The data indicate that obesity is a risk factor for venous thromboembolic disease in men as well as women.
期刊介绍：
The American Journal of Medicine - "The Green Journal" - publishes original clinical research of interest to physicians in internal medicine, both in academia and community-based practice. AJM is the official journal of the Alliance for Academic Internal Medicine, a prestigious group comprising internal medicine department chairs at more than 125 medical schools across the U.S. Each issue carries useful reviews as well as seminal articles of immediate interest to the practicing physician, including peer-reviewed, original scientific studies that have direct clinical significance and position papers on health care issues, medical education, and public policy.
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