肯纳德效应有临床证据支持吗?

S Giaquinto, M Mascio, F Di Libero, M Fargnoli, S Pittiglio
{"title":"肯纳德效应有临床证据支持吗?","authors":"S Giaquinto,&nbsp;M Mascio,&nbsp;F Di Libero,&nbsp;M Fargnoli,&nbsp;S Pittiglio","doi":"10.1016/j.archger.2004.04.031","DOIUrl":null,"url":null,"abstract":"<p><p>The objective of the study was to evaluate the so-called Kennard effect, i.e., the existence of a negative correlation between recovery and age. Thirty-eight elderly patients(median age 71 years, range 60-81) suffering from their first stroke were enrolled. The mean interval since the stroke was 15 days. Patients entered a 60-day rehabilitation pro -gram. Their functional condition was assessed by means of the functional independence measure (FIM). Only FIM values under 36 at admission were considered. Computerized tomographic (CT) or magnetic resonance imaging (MRI) scans were performed in all cases. The type of lesion was ischemic in 24 cases, hemorrhagic in 7 cases and 7 cases had more than one lesion. The patients' families were contacted after one year for a follow-up and all of them gave their consent. The survivors were examined again. The FIM score at discharge and the corresponding values at follow-up were statistically compared by means of Wilcoxon test (two-tailed). The FIM value at admission of the whole population had the median value of 27.5. None of these patients died during their stay at our rehabilitation center and their median FIM value at discharge was 34.5, a value still indicating high disability. After one year, 22 were still alive at home (57.9 %). Their FIM median value was 46. The difference was significant compared to discharge (Z = -3.228, p = 0.001). Three patients scored 85, 87 and 88, respectively, although none of them received rehabilitation treatment. In conclusion, our results indicate that restorative processes are still active in elderly patients, despite previous stroke and existing comorbidities. Some of the elderly patients of our group could approach to independence, although they displayed a very low FIM value at admission.</p>","PeriodicalId":77833,"journal":{"name":"Archives of gerontology and geriatrics. Supplement","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.archger.2004.04.031","citationCount":"1","resultStr":"{\"title\":\"Is the Kennard effect supported by clinical evidence?\",\"authors\":\"S Giaquinto,&nbsp;M Mascio,&nbsp;F Di Libero,&nbsp;M Fargnoli,&nbsp;S Pittiglio\",\"doi\":\"10.1016/j.archger.2004.04.031\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The objective of the study was to evaluate the so-called Kennard effect, i.e., the existence of a negative correlation between recovery and age. Thirty-eight elderly patients(median age 71 years, range 60-81) suffering from their first stroke were enrolled. The mean interval since the stroke was 15 days. Patients entered a 60-day rehabilitation pro -gram. Their functional condition was assessed by means of the functional independence measure (FIM). Only FIM values under 36 at admission were considered. Computerized tomographic (CT) or magnetic resonance imaging (MRI) scans were performed in all cases. The type of lesion was ischemic in 24 cases, hemorrhagic in 7 cases and 7 cases had more than one lesion. The patients' families were contacted after one year for a follow-up and all of them gave their consent. The survivors were examined again. The FIM score at discharge and the corresponding values at follow-up were statistically compared by means of Wilcoxon test (two-tailed). The FIM value at admission of the whole population had the median value of 27.5. None of these patients died during their stay at our rehabilitation center and their median FIM value at discharge was 34.5, a value still indicating high disability. After one year, 22 were still alive at home (57.9 %). Their FIM median value was 46. The difference was significant compared to discharge (Z = -3.228, p = 0.001). Three patients scored 85, 87 and 88, respectively, although none of them received rehabilitation treatment. In conclusion, our results indicate that restorative processes are still active in elderly patients, despite previous stroke and existing comorbidities. Some of the elderly patients of our group could approach to independence, although they displayed a very low FIM value at admission.</p>\",\"PeriodicalId\":77833,\"journal\":{\"name\":\"Archives of gerontology and geriatrics. Supplement\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.archger.2004.04.031\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of gerontology and geriatrics. Supplement\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/j.archger.2004.04.031\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of gerontology and geriatrics. Supplement","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.archger.2004.04.031","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

该研究的目的是评估所谓的肯纳德效应,即康复与年龄之间存在负相关关系。38例首次中风的老年患者(中位年龄71岁,范围60-81岁)被纳入研究。中风后的平均间隔时间为15天。患者进入了一个为期60天的康复计划。采用功能独立性测量法(FIM)评价其功能状态。仅考虑入学时低于36的FIM值。所有病例均行计算机断层扫描(CT)或磁共振成像(MRI)扫描。病灶类型为缺血性24例,出血性7例,多发病灶7例。一年后,我们联系了患者家属进行随访,他们都表示同意。幸存者再次接受了检查。出院时的FIM评分与随访时的FIM评分采用Wilcoxon检验(双侧)进行统计学比较。整个人群入院时的FIM值中位数为27.5。这些患者在我们康复中心住院期间均未死亡,出院时FIM值中位数为34.5,该值仍然表明残疾程度高。一年后,22人仍在家中存活(57.9%)。他们的FIM中位数为46。与出院组比较差异有统计学意义(Z = -3.228, p = 0.001)。三名患者的得分分别为85分、87分和88分,尽管他们都没有接受康复治疗。总之,我们的研究结果表明,尽管有既往卒中和现有合并症,老年患者的恢复性过程仍然活跃。本组部分老年患者虽入院时FIM值很低,但仍可接近独立生活。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is the Kennard effect supported by clinical evidence?

The objective of the study was to evaluate the so-called Kennard effect, i.e., the existence of a negative correlation between recovery and age. Thirty-eight elderly patients(median age 71 years, range 60-81) suffering from their first stroke were enrolled. The mean interval since the stroke was 15 days. Patients entered a 60-day rehabilitation pro -gram. Their functional condition was assessed by means of the functional independence measure (FIM). Only FIM values under 36 at admission were considered. Computerized tomographic (CT) or magnetic resonance imaging (MRI) scans were performed in all cases. The type of lesion was ischemic in 24 cases, hemorrhagic in 7 cases and 7 cases had more than one lesion. The patients' families were contacted after one year for a follow-up and all of them gave their consent. The survivors were examined again. The FIM score at discharge and the corresponding values at follow-up were statistically compared by means of Wilcoxon test (two-tailed). The FIM value at admission of the whole population had the median value of 27.5. None of these patients died during their stay at our rehabilitation center and their median FIM value at discharge was 34.5, a value still indicating high disability. After one year, 22 were still alive at home (57.9 %). Their FIM median value was 46. The difference was significant compared to discharge (Z = -3.228, p = 0.001). Three patients scored 85, 87 and 88, respectively, although none of them received rehabilitation treatment. In conclusion, our results indicate that restorative processes are still active in elderly patients, despite previous stroke and existing comorbidities. Some of the elderly patients of our group could approach to independence, although they displayed a very low FIM value at admission.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信