M Pi-Figueras, A Aguilera, M Arellano, R Miralles, P Garcia-Caselles, R Torres, A M Cervera
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The precipitating factors in the studied population were the following: changing environmental influences in 66 patients(97%) (15 with delirium and 51 without delirium); other drugs 56 (82.3 %) (11 vs. 45);others 56 (82.3%) (9 vs. 24); psychoactive medications 50 (73.5%) (12 vs. 38); acute infections 48 (70.5 %) (13 vs. 35); metabolic disorders/anemia 40 (58.8 %) (9 vs. 31); major surgery-ICU stay 28 (41 .1%) (8 vs. 20); severe pain 26 (38.2%) (6 vs. 20); pulmonary and heart failure 22 (32.3%) (5 vs. 17). The univariant analysis showed that, none of the precipitating factors studied was significantly related to delirium. Seventy-two patients (91.1%) had simultaneously >3 precipitating factors. There were 16 patients with >6 precipitating factors, 7 of 15 with delirium and 9 of the 53 without delirium (46.6 % vs 16.9 %) (p < 0.05). The prevalence of delirium has been 22 %. Most of the patients had developed delirium before the admission at GCU. 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引用次数: 11
摘要
目的是评估从急症护理医院出院并入住老年康复病房(GCU)的患者谵妄的患病率,并分析患者的特征和危险诱发因素。68例患者在2周的时间内进行了分析。神志不清评定法(CAM)检测谵妄。评估的诱发因素包括:大手术-重症监护病房(ICU)住院、肺和心力衰竭、急性感染、代谢紊乱/贫血、精神活性药物、其他药物、剧烈疼痛、不断变化的环境影响等。根据CAM, 15例患者出现谵妄(22%),其中14例(93.3%)在GCU入院前出现谵妄。研究人群的诱发因素如下:66例(97%)患者的环境影响变化(谵妄15例,非谵妄51例);其他56种(82.3%)(11比45);其他56种(82.3%)(9比24);精神药物50例(73.5%)(12对38);急性感染48例(70.5%)(13例对35例);代谢性疾病/贫血40例(58.8%)(9对31);大手术- icu住院28例(41.1%)(8例对20例);重度疼痛26例(38.2%)(6对20);肺和心力衰竭22例(32.3%)(5 vs. 17)。单变量分析显示,所有诱发因素均与谵妄无显著相关性。72例(91.1%)患者同时存在3个以上的诱发因素。诱发因素>6者16例,伴谵妄者15例中7例,无谵妄者53例中9例(46.6% vs 16.9%),差异有统计学意义(p < 0.05)。谵妄的患病率为22%。多数患者入院前已出现谵妄。较高比例的患者有>3个诱发因素。在本研究中,大于6种沉淀因素同时存在与谵妄有显著关系。
Prevalence of delirium in a geriatric convalescence hospitalization unit: patient's clinical characteristics and risk precipitating factor analysis.
The aim was to evaluate the prevalence of delirium among patients discharged from an acute care hospital and admitted to a geriatric convalescence unit (GCU), and to analyze patient's characteristics and risk precipitating factors. Sixty-eight patients were analyzed during a 2-week period. The confusion assessment method (CAM) was used to detect delirium. The precipitating factors evaluated were: major surgery-intensive care unit(ICU) stay, pulmonary and heart failure, acute infections, metabolic disorders/anemia,psychoactive medications, other drugs, severe pain, changing environmental influences and others. According to CAM, fifteen patients presented delirium (22%), and in 14 of them(93.3 %) the delirium was developed before admission at GCU. The precipitating factors in the studied population were the following: changing environmental influences in 66 patients(97%) (15 with delirium and 51 without delirium); other drugs 56 (82.3 %) (11 vs. 45);others 56 (82.3%) (9 vs. 24); psychoactive medications 50 (73.5%) (12 vs. 38); acute infections 48 (70.5 %) (13 vs. 35); metabolic disorders/anemia 40 (58.8 %) (9 vs. 31); major surgery-ICU stay 28 (41 .1%) (8 vs. 20); severe pain 26 (38.2%) (6 vs. 20); pulmonary and heart failure 22 (32.3%) (5 vs. 17). The univariant analysis showed that, none of the precipitating factors studied was significantly related to delirium. Seventy-two patients (91.1%) had simultaneously >3 precipitating factors. There were 16 patients with >6 precipitating factors, 7 of 15 with delirium and 9 of the 53 without delirium (46.6 % vs 16.9 %) (p < 0.05). The prevalence of delirium has been 22 %. Most of the patients had developed delirium before the admission at GCU. A high proportion of patients had >3 precipitating factors. In the study the presence of > 6 precipitating factors simultaneously has been significantly related to delirium.