Mario Buffelli, Giuseppe Busetto, Carlo Bidoia, Morgana Favero, Alberto Cangiano
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Activity-dependent synaptic competition at mammalian neuromuscular junctions.
Synapse elimination is a widespread developmental process in the peripheral and central nervous system that brings about refinement of neural connections through epigenetic mechanisms. Here we describe recent advances concerning the role of the pattern of motoneuronal firing, synchronous or asynchronous, in neuromuscular synapse elimination.
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