连接蛋白为血管通讯铺平了道路。

Cor De Wit
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引用次数: 71

摘要

小动脉内的协调行为是发生大阻力变化所必需的,并反映为沿小动脉扩张/收缩的传导。这些反应是由局部启动的超极化或去极化引起的,这些超极化或去极化通过由连接蛋白(间隙连接)形成的跨膜通道传播。越来越多的证据表明,缝隙连接通讯有助于控制血管张力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Connexins pave the way for vascular communication.

Coordinated behavior within arterioles is necessary for large resistance changes to occur and is reflected as a conduction of dilations/constrictions along arterioles. These responses arise from locally initiated hyper- or depolarizations that propagate via transmembrane channels formed by connexins (gap junctions). Mounting evidence indicates that gap-junctional communication contributes to the control of vascular tone.

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