[初级保健中的糖尿病、高血压和微量白蛋白尿]。

P Bramlage, H U Wittchen, D Pittrow, R Dikow, W Kirch, H Lehnert, E Ritz
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引用次数: 0

摘要

近年来,微量白蛋白尿已被广泛认为是心血管疾病发病率和死亡率增加的一个有价值的风险标志。因此,德国和美国的2型糖尿病治疗指南建议,一旦确诊为糖尿病,每年进行一次筛查,当出现微量白蛋白尿时,每季度进行一次控制。虽然美国有全国代表性的流行病学数据,但德国的数据,特别是初级保健部门的数据却缺失。鉴于初级保健医生的守门人功能,这一点尤其重要。在“高血压和糖尿病风险筛查研究”(HYDRA)中,37.8%的高血压和糖尿病患者在研究当天微量白蛋白尿试纸试验呈阳性,而其中只有12.5%的患者被医生诊断为肾病。这些患者还表现出相关合并症的高负担,因此需要早期发现和干预,特别是因为有有效的治疗方法。尽管指南中推荐微量白蛋白尿筛查,但在初级保健中常规筛查微量白蛋白尿的价值尚未得到认可。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Diabetes, hypertension and microalbuminuria in primary care].

Microalbuminuria has been widely appreciated in recent years to be a valuable risk marker for an increased cardiovascular disease morbidity and mortality. Thus guidelines for the treatment of type-2-diabetes in Germany and the US recommend an annual screening as soon as the diagnosis of diabetes is established and a quarterly control when microalbuminuria is present. While nationally representative epidemiologic data from the US have been available, data from Germany, especially from the primary care sector are missing. This is especially important in light of the gatekeeper function of the primary care physician. The "Hypertension and Diabetes Risk Screening Study" (HYDRA) has been identifying 37.8% of patients with hypertension and diabetes to have a positive dipstick test for microalbuminuria on the study day while only 12.5% of these are diagnosed by the doctor as having nephropathy. These patients additionally show a high burden of associated comorbidities and thus call for early detection and intervention especially because effective therapy is available. Although screening for microalbuminuria is recommended in the guidelines the value of a routine screening for microalbuminuria in primary care is under recognized.

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