{"title":"[中枢神经系统传染病的病因学]。","authors":"Jun-long Yu, Shui-ping Liu, Min-hua Luo","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To determine the etiological characteristics of infectious diseases in the central neural system (CNS).</p><p><strong>Methods: </strong>The serum and cerebral spinal fluid of acute patients in the CNS were detected for virus-specific IgM, IgG and pathogens with enzyme-linked immunosorbent assay as well as traditional bacterial and fungal culture.</p><p><strong>Results: </strong>Of the 823 patients, 126 (15.3%) patients were positive herpes simplex virus (HSV)-specific IgM and/or IgG, of which the maximum morbidity was under 10 years; 10(1.2%) were positive cytomegalovirus specific IgM and/or IgG; 8 (0.97%) were positive varicella-zoster virus specific IgM and/or IgG; 7 (0.85%) were diagnosed as tubercular meningitis; 6 (0.72%) as cryptocococes meningitis and 1 (0.12%) as meningococcic meningitis.</p><p><strong>Conclusion: </strong>Viruses, especially herpes simplex viruses are the common causative agents of infectious diseases of the CNS, in which mycobacterium tuberculosis and cryptocococcus neoformans are conspicuous.</p>","PeriodicalId":13115,"journal":{"name":"Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University","volume":"28 4","pages":"412-4"},"PeriodicalIF":0.0000,"publicationDate":"2003-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Etiology of infectious diseases in the central nervous system].\",\"authors\":\"Jun-long Yu, Shui-ping Liu, Min-hua Luo\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To determine the etiological characteristics of infectious diseases in the central neural system (CNS).</p><p><strong>Methods: </strong>The serum and cerebral spinal fluid of acute patients in the CNS were detected for virus-specific IgM, IgG and pathogens with enzyme-linked immunosorbent assay as well as traditional bacterial and fungal culture.</p><p><strong>Results: </strong>Of the 823 patients, 126 (15.3%) patients were positive herpes simplex virus (HSV)-specific IgM and/or IgG, of which the maximum morbidity was under 10 years; 10(1.2%) were positive cytomegalovirus specific IgM and/or IgG; 8 (0.97%) were positive varicella-zoster virus specific IgM and/or IgG; 7 (0.85%) were diagnosed as tubercular meningitis; 6 (0.72%) as cryptocococes meningitis and 1 (0.12%) as meningococcic meningitis.</p><p><strong>Conclusion: </strong>Viruses, especially herpes simplex viruses are the common causative agents of infectious diseases of the CNS, in which mycobacterium tuberculosis and cryptocococcus neoformans are conspicuous.</p>\",\"PeriodicalId\":13115,\"journal\":{\"name\":\"Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University\",\"volume\":\"28 4\",\"pages\":\"412-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2003-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Etiology of infectious diseases in the central nervous system].
Objective: To determine the etiological characteristics of infectious diseases in the central neural system (CNS).
Methods: The serum and cerebral spinal fluid of acute patients in the CNS were detected for virus-specific IgM, IgG and pathogens with enzyme-linked immunosorbent assay as well as traditional bacterial and fungal culture.
Results: Of the 823 patients, 126 (15.3%) patients were positive herpes simplex virus (HSV)-specific IgM and/or IgG, of which the maximum morbidity was under 10 years; 10(1.2%) were positive cytomegalovirus specific IgM and/or IgG; 8 (0.97%) were positive varicella-zoster virus specific IgM and/or IgG; 7 (0.85%) were diagnosed as tubercular meningitis; 6 (0.72%) as cryptocococes meningitis and 1 (0.12%) as meningococcic meningitis.
Conclusion: Viruses, especially herpes simplex viruses are the common causative agents of infectious diseases of the CNS, in which mycobacterium tuberculosis and cryptocococcus neoformans are conspicuous.
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