{"title":"重组生长激素治疗肝硬化合并低蛋白血症的临床观察","authors":"Shao-jun Liu, Wu-liang Tang, Shou-rong Shen","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To assess the effect of recombinant growth hormone (rhGH) therapy for liver cirrhosis patients with hypoproteinemia.</p><p><strong>Methods: </strong>Fifteen patients with liver cirrhosis were treated with rhGH (4 U per day) for 7 days and 15 controls were given human albumin (10 g) for every other day (altogether 3 times). Albumin was measured one day before the treatment, and on day 1, 10, 14, and 28 after the treatment.</p><p><strong>Results: </strong>After 7 days of rhGH administration, the albumin level of the patients was significantly higher and the function lasted longer than those of patients treated with human albumin (P < 0.05).</p><p><strong>Conclusion: </strong>Exogenous rhGH in treating hypoproteinemia in patients with liver cirrhosis is more effective than human albumin.</p>","PeriodicalId":13115,"journal":{"name":"Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University","volume":"28 4","pages":"398-400"},"PeriodicalIF":0.0000,"publicationDate":"2003-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Clinical observation of recombinant growth hormone therapy for liver cirrhosis with hypoproteinemia].\",\"authors\":\"Shao-jun Liu, Wu-liang Tang, Shou-rong Shen\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To assess the effect of recombinant growth hormone (rhGH) therapy for liver cirrhosis patients with hypoproteinemia.</p><p><strong>Methods: </strong>Fifteen patients with liver cirrhosis were treated with rhGH (4 U per day) for 7 days and 15 controls were given human albumin (10 g) for every other day (altogether 3 times). Albumin was measured one day before the treatment, and on day 1, 10, 14, and 28 after the treatment.</p><p><strong>Results: </strong>After 7 days of rhGH administration, the albumin level of the patients was significantly higher and the function lasted longer than those of patients treated with human albumin (P < 0.05).</p><p><strong>Conclusion: </strong>Exogenous rhGH in treating hypoproteinemia in patients with liver cirrhosis is more effective than human albumin.</p>\",\"PeriodicalId\":13115,\"journal\":{\"name\":\"Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University\",\"volume\":\"28 4\",\"pages\":\"398-400\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2003-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:探讨重组生长激素(rhGH)治疗肝硬化合并低蛋白血症的疗效。方法:15例肝硬化患者给予rhGH (4 U / d)治疗7 d,对照组15例给予人白蛋白(10 g / d)治疗,共3次。治疗前1天及治疗后第1、10、14、28天测定白蛋白。结果:rhGH给药7 d后,患者白蛋白水平明显高于人白蛋白组,且功能持续时间较人白蛋白组延长(P < 0.05)。结论:外源性rhGH治疗肝硬化低蛋白血症的疗效优于人白蛋白。
[Clinical observation of recombinant growth hormone therapy for liver cirrhosis with hypoproteinemia].
Objective: To assess the effect of recombinant growth hormone (rhGH) therapy for liver cirrhosis patients with hypoproteinemia.
Methods: Fifteen patients with liver cirrhosis were treated with rhGH (4 U per day) for 7 days and 15 controls were given human albumin (10 g) for every other day (altogether 3 times). Albumin was measured one day before the treatment, and on day 1, 10, 14, and 28 after the treatment.
Results: After 7 days of rhGH administration, the albumin level of the patients was significantly higher and the function lasted longer than those of patients treated with human albumin (P < 0.05).
Conclusion: Exogenous rhGH in treating hypoproteinemia in patients with liver cirrhosis is more effective than human albumin.