化学发光免疫法与免疫放射法检测血清TSH的临床价值比较。

Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University Pub Date : 2003-06-01

Jian-ying Yu, Ying Lin

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引用次数: 0

摘要

目的:比较化学发光免疫法(CLIA)与免疫放射法(IRMA)检测甲亢、甲减患者TSH的临床价值。方法:对112例正常人、120例甲亢患者和58例甲减患者的血清TSH水平进行了CLIA和IRMA检测。结果:CLIA与IRMA有显著相关性(r = 0.98, P < 0.01)。CLIA诊断甲状腺功能亢进和甲状腺功能减退的符合率高于IRMA，且CLIA的准确性和重复性高于IRMA。结论:CLIA对甲状腺功能亢进和甲状腺功能减退的诊断价值高于IRMA。

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[Clinical value comparison between chemiluminescent immunoassay and immunoradiometric assay in detecting TSH in serum].

Objective: To compare the clinical value between chemiluminescent immunoassay (CLIA) and immunoradiometric assay (IRMA) in detecting TSH in patients with hyperthyroidism and hypothyroidism.

Methods: The TSH levels in serums were detected by CLIA and IRMA in 112 normal persons, 120 hyperthyroidism patients and 58 hypothyroidism patients.

Results: CLIA was significantly correlated with IRMA (r = 0.98, P < 0.01). CLIA had higher coincidence rate than IRMA in the diagnosis of hyperthyroidism and hypothyroidism, and CLIA was more accurate and repetitive than IRMA.

Conclusion: CLIA is more valuable than IRMA in diagnosing both hyperthyroidism and hypothyroidism.

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Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University

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