游泳运动对大鼠脑、肝、心脂质过氧化的影响。

Günfer Turgut, Süleyman Demir, Osman Genç, Ismail Karabulut, Nalan Akalin
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引用次数: 0

摘要

本研究旨在研究游泳运动对脑、肝和心脏氧化最后产物丙二醛(MDA)水平的影响,并将其与对照组脑、肝和心脏MDA水平进行比较。实验选用20只Wistar大鼠,随机饲喂标准实验室饲料。将大鼠分为两组,对照组(n = 10)和运动组(n = 10)。运动组大鼠进行30分钟的游泳运动。每组动物被斩首后,迅速切除大脑、肝脏和心脏组织。根据丙二醛与硫代巴比妥酸反应的方法测定脑、肝、心的丙二醛水平。采用Mann-Whitney U检验对结果进行评价。运动组肝脏和心脏MDA水平(分别为29.59+/-6.73和10.49+/-1.90 nmol/g组织)显著高于对照组(21.78+/-3.46和8.86+/-1.25 nmol/g组织,p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The effect of swimming exercise on lipid peroxidation in the rat brain, liver and heart.

We intended to study the effect of swimming exercise on the brain, liver and heart malondialdehyde (MDA) levels which are the last product of oxidation, and to compare them with the brain, liver and heart MDA levels of controls. The experiments were carried out on 20 Wistar rats which were fed with a standard laboratory chow diet ad libitum. Rats were distributed in two groups, control group (n = 10) and exercise group (n = 10). The exercise group rats were exposed to swimming exercise for 30 minutes. After this animals in each group were sacrificed by decapitation, their brain, liver and heart tissues were quickly removed. MDA levels of the brain, liver and heart were determined according to the method in which MDA reacts with thiobarbituric acid. Results were evaluated by the Mann-Whitney U test. The liver and heart MDA levels in the exercise group were (29.59+/-6.73 and 10.49+/-1.90 nmol/g tissue, respectively) significantly higher than in the control group (21.78+/-3.46 and 8.86+/-1.25 nmol/g tissue, p<0.01 and p<0.05, respectively). However, the brain MDA levels were similar in both groups (exercise group 19.37+/-5.50 nmol/g tissue and control group 16.58+/-2.44 nmol/g tissue; p=0.325). It is concluded that swimming exercise might cause oxidative stress.

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