{"title":"超声辐照脑脂质在水介质中的分散","authors":"D.B. Gammack, J.H. Perrin, L. Saunders","doi":"10.1016/0926-6542(64)90127-1","DOIUrl":null,"url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Optcally-clear sols of ox-brain cerebral lipids prepared by ultrasonic irradiation (16–24 kcycles/sec) have been examined by physicochemical methods.</p></span></li><li><span>2.</span><span><p>2. The myelinic figures in the lecithin sols were broken down to disc-shaped micelles with a micellar weight of about 2·10<sup>6</sup>.</p></span></li><li><span>3.</span><span><p>3. Sedimentation of dispersions of phosphatidylethanolamine and -serine and sphingomyelin indicated micellar weights similar to that for lecithin.</p></span></li><li><span>4.</span><span><p>4. The phospholipid sols, with the exception of phosphatidylethanolamine, were stable over several days and were not flocculated by dilute salt solutions.</p></span></li><li><span>5.</span><span><p>5. Sulphatides, unlike cerebrosides, were readily dispersed, due to the acidic groups on the molecules.</p></span></li><li><span>6.</span><span><p>6. No evidence for chemical changes resulting from ultrasonic irradiation was obtained from preliminary analyses.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 5","pages":"Pages 576-586"},"PeriodicalIF":0.0000,"publicationDate":"1964-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90127-1","citationCount":"25","resultStr":"{\"title\":\"The dispersion of cerebral lipids in aqueous media by ultrasonic irradiation\",\"authors\":\"D.B. Gammack, J.H. Perrin, L. Saunders\",\"doi\":\"10.1016/0926-6542(64)90127-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p></p><ul><li><span>1.</span><span><p>1. Optcally-clear sols of ox-brain cerebral lipids prepared by ultrasonic irradiation (16–24 kcycles/sec) have been examined by physicochemical methods.</p></span></li><li><span>2.</span><span><p>2. The myelinic figures in the lecithin sols were broken down to disc-shaped micelles with a micellar weight of about 2·10<sup>6</sup>.</p></span></li><li><span>3.</span><span><p>3. Sedimentation of dispersions of phosphatidylethanolamine and -serine and sphingomyelin indicated micellar weights similar to that for lecithin.</p></span></li><li><span>4.</span><span><p>4. The phospholipid sols, with the exception of phosphatidylethanolamine, were stable over several days and were not flocculated by dilute salt solutions.</p></span></li><li><span>5.</span><span><p>5. Sulphatides, unlike cerebrosides, were readily dispersed, due to the acidic groups on the molecules.</p></span></li><li><span>6.</span><span><p>6. No evidence for chemical changes resulting from ultrasonic irradiation was obtained from preliminary analyses.</p></span></li></ul></div>\",\"PeriodicalId\":100171,\"journal\":{\"name\":\"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects\",\"volume\":\"84 5\",\"pages\":\"Pages 576-586\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1964-10-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0926-6542(64)90127-1\",\"citationCount\":\"25\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0926654264901271\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0926654264901271","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The dispersion of cerebral lipids in aqueous media by ultrasonic irradiation
1.
1. Optcally-clear sols of ox-brain cerebral lipids prepared by ultrasonic irradiation (16–24 kcycles/sec) have been examined by physicochemical methods.
2.
2. The myelinic figures in the lecithin sols were broken down to disc-shaped micelles with a micellar weight of about 2·106.
3.
3. Sedimentation of dispersions of phosphatidylethanolamine and -serine and sphingomyelin indicated micellar weights similar to that for lecithin.
4.
4. The phospholipid sols, with the exception of phosphatidylethanolamine, were stable over several days and were not flocculated by dilute salt solutions.
5.
5. Sulphatides, unlike cerebrosides, were readily dispersed, due to the acidic groups on the molecules.
6.
6. No evidence for chemical changes resulting from ultrasonic irradiation was obtained from preliminary analyses.
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