{"title":"人α-脂蛋白与红细胞之间的脂质转移","authors":"L.A.E. Ashworth, C. Green","doi":"10.1016/0926-6542(64)90075-7","DOIUrl":null,"url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. The transfer of palmitic acid and sterol between human α-lipoprotein and erythrocytes has been studied.</p></span></li><li><span>2.</span><span><p>2. Human erythrocytes take up palmitic acid from α-lipoprotein until all binding sites are filled. The process is very much more rapid if the lipoprotein also extra cholesterol.</p></span></li><li><span>3.</span><span><p>3. 38% of the endotenous unesterified sterol of human α-lipoprotein does not exchange with that of rat erythrocytes.</p></span></li><li><span>4.</span><span><p>4. [<sup>14</sup>C]Cholesterol taken up by the lipoprotein after dispersion on Celite exchanges with that of human erythrocytes but it does not behave in exactly the same way as the endogenous sterol.</p></span></li><li><span>5.</span><span><p>5. When α-lipoprotein is labelled with both cholesterol and palmitic acid and then incubated with human erythrocytes, each interferes with the transfer, to the cells, of the other.</p></span></li></ul></div>","PeriodicalId":100171,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","volume":"84 2","pages":"Pages 182-187"},"PeriodicalIF":0.0000,"publicationDate":"1964-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6542(64)90075-7","citationCount":"30","resultStr":"{\"title\":\"The transfer of lipids between human α-lipoprotein and erythrocytes\",\"authors\":\"L.A.E. Ashworth, C. Green\",\"doi\":\"10.1016/0926-6542(64)90075-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p></p><ul><li><span>1.</span><span><p>1. The transfer of palmitic acid and sterol between human α-lipoprotein and erythrocytes has been studied.</p></span></li><li><span>2.</span><span><p>2. Human erythrocytes take up palmitic acid from α-lipoprotein until all binding sites are filled. The process is very much more rapid if the lipoprotein also extra cholesterol.</p></span></li><li><span>3.</span><span><p>3. 38% of the endotenous unesterified sterol of human α-lipoprotein does not exchange with that of rat erythrocytes.</p></span></li><li><span>4.</span><span><p>4. [<sup>14</sup>C]Cholesterol taken up by the lipoprotein after dispersion on Celite exchanges with that of human erythrocytes but it does not behave in exactly the same way as the endogenous sterol.</p></span></li><li><span>5.</span><span><p>5. When α-lipoprotein is labelled with both cholesterol and palmitic acid and then incubated with human erythrocytes, each interferes with the transfer, to the cells, of the other.</p></span></li></ul></div>\",\"PeriodicalId\":100171,\"journal\":{\"name\":\"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects\",\"volume\":\"84 2\",\"pages\":\"Pages 182-187\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1964-04-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0926-6542(64)90075-7\",\"citationCount\":\"30\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0926654264900757\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0926654264900757","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The transfer of lipids between human α-lipoprotein and erythrocytes
1.
1. The transfer of palmitic acid and sterol between human α-lipoprotein and erythrocytes has been studied.
2.
2. Human erythrocytes take up palmitic acid from α-lipoprotein until all binding sites are filled. The process is very much more rapid if the lipoprotein also extra cholesterol.
3.
3. 38% of the endotenous unesterified sterol of human α-lipoprotein does not exchange with that of rat erythrocytes.
4.
4. [14C]Cholesterol taken up by the lipoprotein after dispersion on Celite exchanges with that of human erythrocytes but it does not behave in exactly the same way as the endogenous sterol.
5.
5. When α-lipoprotein is labelled with both cholesterol and palmitic acid and then incubated with human erythrocytes, each interferes with the transfer, to the cells, of the other.
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