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引用次数: 74
摘要
FXYD家族的蛋白作为na - k - atp酶的组织特异性调节因子。它们是一种小的疏水性I型蛋白，具有单跨膜跨度，含有胞外不变的FXYD序列。FXYD蛋白不是na - k - atp酶的组成部分，而是通过与特定na - k - atp酶结构域的分子相互作用来调节na - k - atp酶的催化性能。
Functional modulation of the sodium pump: the regulatory proteins "Fixit".
Proteins of the FXYD family act as tissue-specific regulators of the Na-K-ATPase. They are small hydrophobic type I proteins with a single-transmembrane span containing an extracellular invariant FXYD sequence. FXYD proteins are not an integral part of the Na-K-ATPase but function to modulate its catalytic properties by molecular interactions with specific Na-K-ATPase domains.
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