{"title":"淋巴细胞重新排列、编辑和修改它们的抗原受体，使其有用而又安全","authors":"Pamela J. Fink , Catherine J. McMahan","doi":"10.1016/S0167-5699(00)01734-5","DOIUrl":null,"url":null,"abstract":"<div><p>Pamela Fink and Catherine McMahan discuss how B and T cells test for useful antigen receptors and weed out potentially harmful ones, with special attention paid to T-cell receptor revision, a newly described mechanism by which mature T cells can maintain self tolerance.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 11","pages":"Pages 561-566"},"PeriodicalIF":0.0000,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01734-5","citationCount":"61","resultStr":"{\"title\":\"Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe\",\"authors\":\"Pamela J. Fink , Catherine J. McMahan\",\"doi\":\"10.1016/S0167-5699(00)01734-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Pamela Fink and Catherine McMahan discuss how B and T cells test for useful antigen receptors and weed out potentially harmful ones, with special attention paid to T-cell receptor revision, a newly described mechanism by which mature T cells can maintain self tolerance.</p></div>\",\"PeriodicalId\":73346,\"journal\":{\"name\":\"Immunology today\",\"volume\":\"21 11\",\"pages\":\"Pages 561-566\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2000-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01734-5\",\"citationCount\":\"61\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Immunology today\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0167569900017345\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunology today","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167569900017345","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe
Pamela Fink and Catherine McMahan discuss how B and T cells test for useful antigen receptors and weed out potentially harmful ones, with special attention paid to T-cell receptor revision, a newly described mechanism by which mature T cells can maintain self tolerance.
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