经颅刺激显示局灶性运动性癫痫和皮质肌阵挛患者皮质兴奋性的不对称性

Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control Pub Date : 1998-02-01 DOI:10.1016/S0924-980X(97)00062-3

Maurizio Inghilleri , Donatella Mattia , Alfredo Berardelli , Mario Manfredi

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引用次数: 44

摘要

应用经颅刺激分析了一例运动局灶性癫痫伴右侧运动皮质肌阵挛患者的运动皮质兴奋性。单次经颅磁刺激而非电刺激的运动阈值在癫痫运动皮层中高于正常左运动皮层。单次磁刺激在癫痫运动皮层中引起短暂的皮层沉默期(50 ms)。配对磁刺激也显示皮质-皮质抑制减弱。这些发现揭示了皮层兴奋性的不对称性，可能是由于癫痫运动皮层的抑制受损

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Asymmetry of cortical excitability revealed by transcranial stimulation in a patient with focal motor epilepsy and cortical myoclonus

Motor cortex excitability was analyzed with transcranial stimulation in a patient with motor focal epilepsy and cortical myoclonus originating from the right motor cortex. The motor threshold to single transcranial magnetic shocks, but not to electric stimuli, was higher in the epileptic motor cortex than the normal left motor cortex. Single magnetic shocks elicited a short cortical silent period (50 ms) in the epileptic motor cortex. Paired magnetic stimuli also showed reduced cortico-cortical inhibition. These findings reveal an asymmetry in cortical excitability presumably due to impaired inhibition in the epileptic motor cortex

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Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control

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