硫酸镁对大鼠学习、情绪及自发运动的影响。

V Lupu, M Dorofteiu
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引用次数: 0

摘要

实验分为三组,每组10只雄性Wistar大鼠,体重110 ~ 130 g:第一组为对照组;2组,硫酸镁100mg /kg体/天ig;第三组,双剂量硫酸镁(200 mg/kg体/天)灌胃。在9天的时间里,对所有动物进行野外情绪和自发运动的测试,以及在穿梭箱中获得主动回避条件反射的能力的测试。无论给药剂量如何,硫酸镁均显著降低了小鼠的学习能力,降低了小鼠的情绪评分,只有双剂量组才显著提高了小鼠的自发运动评分。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of magnesium sulfate on learning, emotivity and spontaneous motility in rats.

The study was performed on three groups, each including 10 male Wistar rats, weighing 110-130 g: group 1, the control group; group 2, animals treated with magnesium sulfate in a dose of 100 mg/kg body/day i.m.; group 3, animals treated with double dose of magnesium sulfate (200 mg/kg body/day i.m.). All animals were tested for emotivity and spontaneous motility in the open field, as well as for their capacity of acquiring active avoidance conditioned reflexes in the shuttle-box, for 9 days. Magnesium sulfate decreased significantly the learning ability, decreased emotivity scores regardless of the administered dose, and increased significantly spontaneous motility scores only in the double dose treated group.

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