S E Tropman, T Hatzell, E Paskett, T Ricketts, M R Cooper, T Aldrich
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引用次数: 0
摘要
本研究旨在确定 1991 年和 1996 年南卡罗来纳州和北卡罗来纳州农村地区的结肠癌治疗在多大程度上符合国家治疗建议。数据来自居住在北卡罗来纳州和南卡罗来纳州农村地区的结肠癌患者的医疗记录。美国国家癌症研究所(National Cancer Institute)的医生数据查询(PDQ)数据库被用来定义最先进的治疗方法,并对接受初级和/或辅助治疗的情况进行分类。采用卡方检验(chi-square)和费雪精确检验(Fisher's exact)评估了治疗随时间、地点和阶段的变化,以及治疗与选定协变量之间的双变量关系。回归法用于控制患者和/或疾病特征与治疗之间可能存在的相互作用。大多数结肠癌病例都接受了初级治疗,这与所研究的其他因素没有明显关系。在提供辅助治疗方面存在差异。III 期患者接受辅助治疗的频率明显高于 II 期患者(p
Colon cancer treatment in rural North and South Carolina.
The purpose of this study was to determine the degree to which colon cancer treatment in rural North and South Carolina in 1991 and 1996 conformed to national treatment recommendations. Data came from medical records of colon cancer patients residing in rural North and South Carolina. The National Cancer Institute's Physician Data Query (PDQ) database was used to define state-of-the-art care and to categorize receipt of primary and/or adjuvant treatment. Changes in treatment over time, location, and stage and bivariate relationships between treatment and selected covariates were assessed with chi-square and Fisher's exact tests. Regression was used to control for possible interactions between patient and/or disease characteristics and treatment. The majority of colon cancer cases received primary therapy as suggested by the PDQ which was not significantly related to other factors examined. There was variation in provision of adjuvant therapy. Stage III patients received adjuvant therapy significantly more often than did stage II patients (p = 0.01). Receipt of appropriate adjuvant therapy among stage III patients was significantly associated with younger patient age and white race (p = 0.05). Rural colon cancer patients are likely to receive primary therapy as recommended by the PDQ, but may be less likely to receive suggested adjuvant therapy. Further understanding of variations in the rate of adjuvant therapy for colon cancer is needed to ensure appropriate treatment regimens are obtained for rural colon cancer patients.