突变扫描的酶法

Graham R. Taylor , Jayne Deeble
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引用次数: 23

摘要

酶促突变扫描方法仍然缺乏化学错配裂解法的敏感性和特异性。然而,我们对错配识别过程的理解的发展应该会导致改进。一些有希望的候选存在更具体和敏感的突变检测潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Enzymatic methods for mutation scanning

Enzymatic methods for mutation scanning still lack the sensitivity and specificity of the chemical cleavage of mismatch method. However developments in our understanding of the mismatch recognition process should lead to improvements. Several promising candidates exist with potential for more specific and sensitive mutation detection.

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