实验性异种神经移植的遗传方法。

Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress Pub Date : 1998-01-01

D Hebebrand, D Wagner, N F Jones, H U Steinau

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摘要

异种移植物的现成可用性和基因工程的前景都可能为外周异种移植提供新的方法。FK506和RS61443能够延长异种神经移植物的存活。在异种组织中加入腺病毒序列可能是降低免疫抑制药物毒性和移植物免疫原性的新选择。

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[Genetic methods in experimental xenogenic nerve transplantation].

The ready availability of xenografts and the promising results of genetic engineering both may offer new methods in peripheral xenotransplantation. FK506 and RS61443 are able to prolong survival of nerve xenografts. The incorporation of adenoviral sequences in xenogeneic tissues is possibly a new option for decreasing the toxicity of immunosuppressive drugs and immunogenicity of grafts.

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Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress

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