[巴西的肝硬化:死亡率和过早失去的有效寿命年]。

I Lessa
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引用次数: 0

摘要

这项描述性研究使用了1989年肝硬化死亡率的官方数据。其目的是:(a)描述巴西成年人肝硬化的死亡率;(b)估计因这一原因过早(在20岁至59岁之间)丧失的生产寿命年数;(c)确定死亡率或PYLL的任何地区差异。原始数据以1980年巴西人口为标准,按年龄和性别进行了调整。PYLL的计算基于Romeder和McWhinnie的潜在寿命损失年数公式,作者对其进行了修改,以表示损失的生产寿命年数。东南部和北部的粗死亡率较高,所有地区的男性粗死亡率都较高,全国男女比为4.5。男性死亡率从中西部的14.37 / 10万到东南部的35.86 / 10万不等;在中西部和北部,女性的发病率分别为3.49至8.5 / 10万。除北方地区外,按年龄划分的男性死亡率曲线在60岁以后呈下降或稳定趋势。对于该地区的男性,曲线继续上升,70岁以后的比率达到86.37 / 10万。女性的曲线也有所上升,在北部和东北部最为明显。年龄调整后的比率显示,东南地区女性的肥胖率有所下降,而北部地区的比率仍然较高。肝硬化死亡率占男性消化系统疾病死亡率的48.7%,占女性消化系统疾病死亡率的24.1%。1989年,138,860例肝硬化患者中,83.2%为男性,而全国的平均年龄约为15.5岁,男女的平均年龄相似。然而,北部男性和女性以及中西部女性的平均PYLL远高于其他地区。数据表明,除北方地区外,所有地区男性的肝硬化都可能是由酗酒引起的。在北方的男性中,有强有力的证据表明,由病毒性病因(乙型和丙型肝炎病毒)引起的肝硬化也存在。对于女性,有证据表明病毒性肝硬化占主导地位。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Liver cirrhosis in Brazil: mortality and productive years of life lost prematurely].

This descriptive study was done using official data on mortality from cirrhosis of the liver for the year 1989. Its objectives were: (a) to describe mortality from cirrhosis of the liver in Brazilian adults; (b) to estimate the productive years of life lost (PYLL) prematurely (between 20 and 59 years of age) from this cause; and (c) to identify any regional differences in mortality or PYLL. The crude data were adjusted by age and sex, using the 1980 population of Brazil as the standard. Calculation of PYLL was based on the formula of Romeder and McWhinnie for years of potential life lost, modified by the author to express productive years of life lost. The crude death rates were higher in the Southeast and North, and in all regions they were higher in males, the countrywide male/female ratio being 4.5. Mortality rates among males varied from 14.37 per 100,000 in the Center-West to 35.86 per 100,000 in the Southeast; for females the rates ranged from 3.49 to 8.5 per 100,000 in the Center-West and North, respectively. The mortality curves by age for men showed a decline or stabilization after age 60, except in the North. For men in that region, the curve continued to rise, and the rate reached 86.37 per 100,000 after age 70. The curves for women also rose, most markedly in the North and Northeast. The age-adjusted rates showed a reduction for women in the Southeast, while rates in the North remained higher. Mortality from cirrhosis of the liver accounted for 48.7% of deaths from disorders of the digestive system among men and 24.1% among women. Of the 138,860 PYLL from cirrhosis of the liver in 1989, 83.2% were lost among males, while the average for the country, around 15.5 years, was similar for both sexes. However, the average PYLL for men and women in the North and women in the Center-West was much higher than in the other regions. The data suggest that cirrhosis of the liver among men in all the regions, except the North, is probably attributable to alcoholism. Among males from the North, there is strong evidence that cirrhosis with a viral etiology (hepatitis B and C virus) also exists. For women, the evidence suggests that cirrhosis of viral etiology predominates.

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