衰老对大鼠脑干核5 -羟色胺能神经元影响的形态学证据。

I S Lolova
{"title":"衰老对大鼠脑干核5 -羟色胺能神经元影响的形态学证据。","authors":"I S Lolova","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effects of age on the 5-hydroxytryptamine-immunoreactive (5-HT-IR) neurons in raphe and extrarapheal nuclei of rats were examined using morphometry. Quantitative parameters of the neuronal density and cross-sectional areas of the cell bodies as well as of the length and numbers of the processes of the 5-HT-IR neurons were analyzed in 3-, 12- and 26-month-old-rats. The results showed that aging affected the 5-HT-IR neurons in the rat brainstem nuclei. The age-related changes in the immunostaining pattern and quantitative parameters were more or less pronounced and earlier or later developed depending on the nucleus studied. It is most probably connected with specific functions and projections of each raphe nucleus.</p>","PeriodicalId":7035,"journal":{"name":"Acta physiologica et pharmacologica Bulgarica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Morphological evidence for effects of the aging on the serotoninergic neurons in the rat brainstem nuclei.\",\"authors\":\"I S Lolova\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The effects of age on the 5-hydroxytryptamine-immunoreactive (5-HT-IR) neurons in raphe and extrarapheal nuclei of rats were examined using morphometry. Quantitative parameters of the neuronal density and cross-sectional areas of the cell bodies as well as of the length and numbers of the processes of the 5-HT-IR neurons were analyzed in 3-, 12- and 26-month-old-rats. The results showed that aging affected the 5-HT-IR neurons in the rat brainstem nuclei. The age-related changes in the immunostaining pattern and quantitative parameters were more or less pronounced and earlier or later developed depending on the nucleus studied. It is most probably connected with specific functions and projections of each raphe nucleus.</p>\",\"PeriodicalId\":7035,\"journal\":{\"name\":\"Acta physiologica et pharmacologica Bulgarica\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta physiologica et pharmacologica Bulgarica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta physiologica et pharmacologica Bulgarica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

采用形态计量学方法观察年龄对大鼠中脑和脑外核5-羟色胺免疫反应神经元的影响。分析3、12、26月龄大鼠5-HT-IR神经元密度、胞体横截面积、突起长度和数量等定量参数。结果表明,衰老对大鼠脑干核内的5-HT-IR神经元有影响。免疫染色模式和定量参数的年龄相关变化或多或少明显,并根据所研究的细胞核而早或晚发展。它很可能与每个中缝核的特定功能和突起有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Morphological evidence for effects of the aging on the serotoninergic neurons in the rat brainstem nuclei.

The effects of age on the 5-hydroxytryptamine-immunoreactive (5-HT-IR) neurons in raphe and extrarapheal nuclei of rats were examined using morphometry. Quantitative parameters of the neuronal density and cross-sectional areas of the cell bodies as well as of the length and numbers of the processes of the 5-HT-IR neurons were analyzed in 3-, 12- and 26-month-old-rats. The results showed that aging affected the 5-HT-IR neurons in the rat brainstem nuclei. The age-related changes in the immunostaining pattern and quantitative parameters were more or less pronounced and earlier or later developed depending on the nucleus studied. It is most probably connected with specific functions and projections of each raphe nucleus.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信