[布良斯克省不同程度铯-137和锶-90土壤污染地区906名儿童血液学和细胞化学筛查结果]。

IF 0.2 4区 医学 Q4 HEMATOLOGY
Gematologiya I Transfuziologiya Pub Date : 1995-11-01
R V Lenskaia, A I Pivovarova, A G Luk'ianova, I A Bykova, G A Zakharova, E V Zelenina, N M Trubina, V M Buiankin, V M Chernov, A A Petrukhin
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引用次数: 0

摘要

居住在布良斯克地区(放射性核素污染0.2-63.9 Cu/km2)的儿童人群的特点是血液计数不一致,尽管相关平均值接近控制值。平均细胞化学指标显示,在所有污染地区的儿童中,成熟t细胞的标志物——点非特异性酯酶(NSEP)的活性显著降低。不同村庄12-33%的儿童通过NSEP试验记录了t淋巴细胞池恢复的细胞化学血淋巴细胞图的变化。NSEP降低10%表明免疫缺陷的适应性和可行性较差。在三分之一的低NSEP患儿中,具有大颗粒PAS反应的淋巴细胞数量可能反映了这些患儿b淋巴生成无效。在两个被铯- 137Cs和锶- 90Sr严重污染的村庄,半数儿童的血红蛋白超过150毫克。三个村庄的儿童淋巴细胞数量急剧上升,伴有强烈的颗粒状PAS反应。这些变化可能与甲状腺异常有关。面临健康恶化风险的儿童人数随着环境污染(137Cs)的增加而增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Results of screening hematological and cytochemical blood studies of 906 children living in Bryansk Province at places with different intensities of soil contamination with cesium-137 and strontium-90].

Populations of children living in the Bryansk territory (radionuclide contamination 0.2-63.9 Cu/km2) are characterized by heterogeneous blood counts, though relevant mean values are close to control. Mean cytochemical indices indicated a significant reduction in activity of point nonspecific esterase (NSEP), a marker of mature T-cells, in children from all the contaminated districts. Shifts in cytochemical blood lymphocytogram by NSEP test evidencing rejuvenascence of T-lymphocyte pool were recorded in 12-33% of children from different villages. A 10% decrease in NSEP suggested poor adaptation and feasibility of immunodeficiency. In one-third of children with low NSEP the number of lymphocytes with large-granular PAS reaction may reflect uneffective B-lymphopoiesis in these children. In two villages significantly contaminated with 137Cs and 90Sr half of the children had blood hemoglobin above 150 milligrams. Children from three villages exhibited a sharp rise in the number of lymphocytes with intensive-granular PAS reaction. These changes may be related to thyroid abnormalities. The number of children at risk of health deterioration grows with growing environmental contamination with 137Cs.

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来源期刊
CiteScore
0.80
自引率
66.70%
发文量
29
审稿时长
>12 weeks
期刊介绍: The journal publishes original theoretical and clinical studies, lectures, reviews, and practical notes concerning various problems of hematology and clinical and industrial transfusion. The journal provides information on the etiology, pathogenesis, diagnosis and treatment of blood disorders as well as on related non-hematological conditions (internal diseases, poisoning, exposure to ionizing radiation etc.).
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