[亚美尼亚人淋巴肉芽肿病与免疫遗传血液标志物的关联分析]。

IF 0.2 4区医学 Q4 HEMATOLOGY

Gematologiya I Transfuziologiya Pub Date : 1995-11-01

V M Nersisian, N O Musaelian, I G Martirosian

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引用次数: 0

摘要

11种免疫遗传血液系统(HLA-A、B - C、DR;土著的;Rh-Hr;mns;基德;Kell-Chellano;达菲;刘易斯;迭戈;通用汽车;对亚美尼亚籍淋巴肉芽肿病(LGM)患者进行了59种抗原的Inv检测。建立了HLA、MNSs和Duffy系统与LGM的致病关系。与HLA表型DR-8、b- 14、b- 21、SS、Fy(a+b-)呈正相关(p < 0.001)。这些表型与LGM有显著相关性(RR = 4.7-2.1)，可作为亚美尼亚人群LGM的遗传标记。

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本刊更多论文

[An analysis of the associational connections of immunogenetic blood markers with lymphogranulomatosis in Armenians].

A study of 11 immunogenetical blood systems (HLA-A, B C, DR; ABO; Rh-Hr; MNSs; Kidd; Kell-Chellano; Duffy; Lewis; Diego; Gm; Inv) involving 59 antigens was performed in patients of Armenian nationality with lymphogranulomatosis (LGM). Pathogenic associations of HLA, MNSs and Duffy systems with LGM were established. Positive correlations were found (p < 0.001) with HLA phenotypes DR-8, B-14, B-21, SS, Fy(a+b-). These phenotypes have significant correlation with LGM (RR = 4.7-2.1) and can be considered as genetic markers of LGM in the Armenian population.

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来源期刊

Gematologiya I Transfuziologiya 医学-血液学

CiteScore

0.80

自引率

66.70%

发文量

审稿时长

>12 weeks

期刊介绍： The journal publishes original theoretical and clinical studies, lectures, reviews, and practical notes concerning various problems of hematology and clinical and industrial transfusion. The journal provides information on the etiology, pathogenesis, diagnosis and treatment of blood disorders as well as on related non-hematological conditions (internal diseases, poisoning, exposure to ionizing radiation etc.).