先前接触汞蒸气的工人的暴露相关指标与神经和神经生理影响的关系。

D G Ellingsen, T Mørland, A Andersen, H Kjuus
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引用次数: 66

摘要

对77名先前暴露于汞蒸气的氯碱工人进行了神经学方面的横断面研究,并与53名年龄匹配的参照物进行了比较。氯碱工人在工作大气中平均暴露于浓度为59微克汞柱/立方米的氯碱7.9年。每年暴露的个体平均尿汞浓度为531 nmol Hg/1。平均而言,在检查前12.3年就停止了接触。正中感觉神经传导速度和腓肠神经振幅都与汞的累积暴露量有关。首次接触汞的年份与视觉诱发反应的各个方面之间也存在关联。先前暴露的体位性震颤或协调性受损的受试者也有视觉诱发反应的改变。这些结果可能表明先前暴露于汞蒸气对神经系统的影响,可能是在视觉通路、小脑和周围感觉神经。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relation between exposure related indices and neurological and neurophysiological effects in workers previously exposed to mercury vapour.

A cross sectional study of aspects of their neurology was carried out on 77 chloralkali workers previously exposed to mercury (Hg) vapour and compared with 53 age matched referents. The chloralkali workers had been exposed for an average of 7.9 years at a concentration of 59 micrograms Hg/m3 in the working atmosphere. The individual mean urinary concentration of Hg for each year of exposure was 531 nmol Hg/1. On average the exposure had ceased 12.3 years before the examinations. Both the median sensory nerve conduction velocity and the amplitude of the sural nerve were associated with measures of cumulative exposure to Hg. An association was also found between years since first exposure to Hg and aspects of the visual evoked response. Previously exposed subjects with postural tremor or impaired coordination also had alterations in visual evoked response. These results may indicate an effect of previous exposure to mercury vapour on the nervous system, possibly in the visual pathway, cerebellum, and the peripheral sensory nerves.

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