{"title":"高效液相色谱法测定大鼠脑中百草枯的含量。","authors":"M T Corasaniti, G Nisticò","doi":"10.1016/0021-9673(93)80578-v","DOIUrl":null,"url":null,"abstract":"<p><p>The applications of a method based on ion-pair solid-phase extraction and reversed-phase HPLC are reported. The method was used to measure paraquat concentrations in discrete brain areas at different times after its systemic administration in rats. In addition, the method was employed in the determination of paraquat levels in whole-brain samples from rats of various ages systemically treated with several doses of the herbicide.</p>","PeriodicalId":15508,"journal":{"name":"Journal of chromatography","volume":"643 1-2","pages":"419-25"},"PeriodicalIF":0.0000,"publicationDate":"1993-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0021-9673(93)80578-v","citationCount":"37","resultStr":"{\"title\":\"Determination of paraquat in rat brain by high-performance liquid chromatography.\",\"authors\":\"M T Corasaniti, G Nisticò\",\"doi\":\"10.1016/0021-9673(93)80578-v\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The applications of a method based on ion-pair solid-phase extraction and reversed-phase HPLC are reported. The method was used to measure paraquat concentrations in discrete brain areas at different times after its systemic administration in rats. In addition, the method was employed in the determination of paraquat levels in whole-brain samples from rats of various ages systemically treated with several doses of the herbicide.</p>\",\"PeriodicalId\":15508,\"journal\":{\"name\":\"Journal of chromatography\",\"volume\":\"643 1-2\",\"pages\":\"419-25\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-07-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0021-9673(93)80578-v\",\"citationCount\":\"37\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of chromatography\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1016/0021-9673(93)80578-v\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of chromatography","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/0021-9673(93)80578-v","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Determination of paraquat in rat brain by high-performance liquid chromatography.
The applications of a method based on ion-pair solid-phase extraction and reversed-phase HPLC are reported. The method was used to measure paraquat concentrations in discrete brain areas at different times after its systemic administration in rats. In addition, the method was employed in the determination of paraquat levels in whole-brain samples from rats of various ages systemically treated with several doses of the herbicide.
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