{"title":"自闭症患者自残行为的精神药理学治疗。","authors":"A Rothenberger","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>This paper is part of a special section on 'self-injurious behavior and autism' and reports new data that variously support the suggested involvement of dopaminergic, serotoninergic and opiatergic neurotransmitter systems in the expression of self-injurious behaviour. Further, some notions concerning the underlying biological mechanisms of self-injurious behaviour related to brain function and brain topography are described. Finally, besides the critical evaluation of several drugs used to treat self-injurious behaviour, four cases of autism are reported where sulpiride, a benzamide derivative, clearly reduced self-injurious behaviour.</p>","PeriodicalId":75409,"journal":{"name":"Acta paedopsychiatrica","volume":"56 2","pages":"99-104"},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Psychopharmacological treatment of self-injurious behavior in individuals with autism.\",\"authors\":\"A Rothenberger\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This paper is part of a special section on 'self-injurious behavior and autism' and reports new data that variously support the suggested involvement of dopaminergic, serotoninergic and opiatergic neurotransmitter systems in the expression of self-injurious behaviour. Further, some notions concerning the underlying biological mechanisms of self-injurious behaviour related to brain function and brain topography are described. Finally, besides the critical evaluation of several drugs used to treat self-injurious behaviour, four cases of autism are reported where sulpiride, a benzamide derivative, clearly reduced self-injurious behaviour.</p>\",\"PeriodicalId\":75409,\"journal\":{\"name\":\"Acta paedopsychiatrica\",\"volume\":\"56 2\",\"pages\":\"99-104\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta paedopsychiatrica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta paedopsychiatrica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Psychopharmacological treatment of self-injurious behavior in individuals with autism.
This paper is part of a special section on 'self-injurious behavior and autism' and reports new data that variously support the suggested involvement of dopaminergic, serotoninergic and opiatergic neurotransmitter systems in the expression of self-injurious behaviour. Further, some notions concerning the underlying biological mechanisms of self-injurious behaviour related to brain function and brain topography are described. Finally, besides the critical evaluation of several drugs used to treat self-injurious behaviour, four cases of autism are reported where sulpiride, a benzamide derivative, clearly reduced self-injurious behaviour.