对d -甲状腺素和多巴胺激动剂有反应的大的生长抑素不敏感的分泌甲状腺激素的垂体瘤。

Acta endocrinologica Pub Date : 1993-10-01 DOI:10.1530/acta.0.1290291

F A Karlsson, P Burman, O Kämpe, J E Westlin, L Wide

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引用次数: 8

摘要

一个独特的促甲状腺激素(TSH)分泌垂体瘤描述了一个病人的历史复发性甲状腺毒症。与先前报道的其他tshoma不同，该肿瘤对生长抑素类似物奥曲肽不敏感。它不积累[111]奥曲肽，但表达功能性多巴胺受体，并对甲状腺素的d -异构体有反应，这两个特征对患者的治疗有益。

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Large somatostatin-insensitive thyrotrophin-secreting pituitary tumour responsive to D-thyroxine and dopamine agonists.

A unique thyrotrophin (TSH)-secreting pituitary tumour is described in a patient with a history of recurrent thyrotoxicosis. Unlike other previously reported TSHomas, the tumour is insensitive to octreotide, a somatostatin analogue. It does not accumulate [111In]octreotide but expresses functional dopamine receptors and responds to the D-isomer of thyroxine, two characteristics beneficial in the management of the patient.

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Acta endocrinologica

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