{"title":"一项在整个欧盟范围内禁止生产、供应和使用所有含氟聚合物和大多数含氟试剂的提案","authors":"Nicholas D. Tyrrell*, ","doi":"10.1021/acs.oprd.3c00199","DOIUrl":null,"url":null,"abstract":"<p >A change to EU law is proposed that would lead to a ban on manufacture, supply, and use of most per- and polyfluorinated alkyl substance (PFAS) materials. The proposed EU definition of PFAS is extremely broad, including most fluoroalkyl materials, regardless of molecular weight. Thus, reagents as simple as trifluoroacetic acid through fluorinated intermediates to polymers such as PTFE, PVDF, and Viton could be entirely banned, with the exception of API molecules themselves. The implications of such a ban for the chemical and (bio)pharma industries in Europe cannot be overstated. The EU Proposal is currently out for public consultation, and the purpose of this Perspective is both to raise awareness and to encourage contributions to the consultation process. Comments to the EU must be received by the <u>deadline of 23:59 (Helsinki time) on September 25, 2023</u>.</p>","PeriodicalId":55,"journal":{"name":"Organic Process Research & Development","volume":"27 8","pages":"1422–1426"},"PeriodicalIF":3.1000,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":"{\"title\":\"A Proposal That Would Ban Manufacture, Supply, and Use of All Fluoropolymers and Most Fluorinated Reagents within the Entire EU\",\"authors\":\"Nicholas D. Tyrrell*, \",\"doi\":\"10.1021/acs.oprd.3c00199\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >A change to EU law is proposed that would lead to a ban on manufacture, supply, and use of most per- and polyfluorinated alkyl substance (PFAS) materials. The proposed EU definition of PFAS is extremely broad, including most fluoroalkyl materials, regardless of molecular weight. Thus, reagents as simple as trifluoroacetic acid through fluorinated intermediates to polymers such as PTFE, PVDF, and Viton could be entirely banned, with the exception of API molecules themselves. The implications of such a ban for the chemical and (bio)pharma industries in Europe cannot be overstated. The EU Proposal is currently out for public consultation, and the purpose of this Perspective is both to raise awareness and to encourage contributions to the consultation process. Comments to the EU must be received by the <u>deadline of 23:59 (Helsinki time) on September 25, 2023</u>.</p>\",\"PeriodicalId\":55,\"journal\":{\"name\":\"Organic Process Research & Development\",\"volume\":\"27 8\",\"pages\":\"1422–1426\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2023-08-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic Process Research & Development\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acs.oprd.3c00199\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Process Research & Development","FirstCategoryId":"92","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acs.oprd.3c00199","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
A Proposal That Would Ban Manufacture, Supply, and Use of All Fluoropolymers and Most Fluorinated Reagents within the Entire EU
A change to EU law is proposed that would lead to a ban on manufacture, supply, and use of most per- and polyfluorinated alkyl substance (PFAS) materials. The proposed EU definition of PFAS is extremely broad, including most fluoroalkyl materials, regardless of molecular weight. Thus, reagents as simple as trifluoroacetic acid through fluorinated intermediates to polymers such as PTFE, PVDF, and Viton could be entirely banned, with the exception of API molecules themselves. The implications of such a ban for the chemical and (bio)pharma industries in Europe cannot be overstated. The EU Proposal is currently out for public consultation, and the purpose of this Perspective is both to raise awareness and to encourage contributions to the consultation process. Comments to the EU must be received by the deadline of 23:59 (Helsinki time) on September 25, 2023.
期刊介绍：
The journal Organic Process Research & Development serves as a communication tool between industrial chemists and chemists working in universities and research institutes. As such, it reports original work from the broad field of industrial process chemistry but also presents academic results that are relevant, or potentially relevant, to industrial applications. Process chemistry is the science that enables the safe, environmentally benign and ultimately economical manufacturing of organic compounds that are required in larger amounts to help address the needs of society. Consequently, the Journal encompasses every aspect of organic chemistry, including all aspects of catalysis, synthetic methodology development and synthetic strategy exploration, but also includes aspects from analytical and solid-state chemistry and chemical engineering, such as work-up tools，process safety, or flow-chemistry. The goal of development and optimization of chemical reactions and processes is their transfer to a larger scale; original work describing such studies and the actual implementation on scale is highly relevant to the journal. However, studies on new developments from either industry, research institutes or academia that have not yet been demonstrated on scale, but where an industrial utility can be expected and where the study has addressed important prerequisites for a scale-up and has given confidence into the reliability and practicality of the chemistry, also serve the mission of OPR&D as a communication tool between the different contributors to the field.
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