发育中的大鼠脑毛细血管周细胞-内皮细胞间隙连接:精细结构研究。

4区医学 Q2 Agricultural and Biological Sciences

Anatomical Record Pub Date : 1995-08-01 DOI:10.1002/ar.1092420412

K Fujimoto

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引用次数: 66

摘要

背景:精细结构研究揭示了大鼠胚胎基底前脑毛细血管中周细胞和内皮细胞之间通过间隙连接的细胞间偶联。结果:周细胞的腔内质膜与内皮细胞的腔内质膜形成间隙连接。结论:间隙连接是直接连接周细胞和内皮细胞细胞质的膜性通道，暗示周细胞对内皮细胞的增殖具有重要作用。据推测，周细胞的功能在产前哺乳动物分配到大脑微循环发育的调节。

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Pericyte-endothelial gap junctions in developing rat cerebral capillaries: a fine structural study.

Background: Fine structural study revealed the intercellular coupling between the pericyte and the endothelial cells via the gap junctions, in the capillaries of the basal forebrain of rat embryos.

Results: Gap junctions were constructed by the adluminal plasmalemma of pericyte and the abluminal plasmalemma of endothelial cells.

Conclusions: Gap junctions are membranous channels that directly join the cytoplasms of the pericyte and endothelial cell and imply some substantial role for the pericyte on the endothelial proliferation. It is postulated that the function of the pericyte in the prenatal mammals are assigned to the regulation of the development of cerebral microcirculation.

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来源期刊

Anatomical Record Agricultural and Biological Sciences-Ecology, Evolution, Behavior and Systematics

CiteScore

4.30

自引率

0.00%

发文量

期刊介绍： The Anatomical Record