{"title":"“双克隆”gammopathies。","authors":"S Ottó, M Börzsönyi, S Eckhardt","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Eleven patients with \"diclonal\" gammopathies have been followed clinically and cytologically in relation to the changes in their serum protein composition. It was observed that the malignant transformation became faster after a second protein had appeared with the appearance of immature lymphoid elements and plasmoblasts. Malignant transformation may occur after long periods of stagnation, therefore a continuous observation of such cases is mandatory.</p>","PeriodicalId":72058,"journal":{"name":"Acta morphologica Academiae Scientiarum Hungaricae","volume":"28 4","pages":"417-34"},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"\\\"Diclonal\\\" gammopathies.\",\"authors\":\"S Ottó, M Börzsönyi, S Eckhardt\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Eleven patients with \\\"diclonal\\\" gammopathies have been followed clinically and cytologically in relation to the changes in their serum protein composition. It was observed that the malignant transformation became faster after a second protein had appeared with the appearance of immature lymphoid elements and plasmoblasts. Malignant transformation may occur after long periods of stagnation, therefore a continuous observation of such cases is mandatory.</p>\",\"PeriodicalId\":72058,\"journal\":{\"name\":\"Acta morphologica Academiae Scientiarum Hungaricae\",\"volume\":\"28 4\",\"pages\":\"417-34\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta morphologica Academiae Scientiarum Hungaricae\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta morphologica Academiae Scientiarum Hungaricae","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Eleven patients with "diclonal" gammopathies have been followed clinically and cytologically in relation to the changes in their serum protein composition. It was observed that the malignant transformation became faster after a second protein had appeared with the appearance of immature lymphoid elements and plasmoblasts. Malignant transformation may occur after long periods of stagnation, therefore a continuous observation of such cases is mandatory.