[Microangiographic and histologic findings in the tibiae of rats after implantation of bone cement (author's transl)].

The reaction of bone tissue to the filling of the medullary cavity with acrylic bone cement was studied in the rat by histological and microangiographic methods. Three months after plugging, the fibrous borderline tissue between cement and bone had changed into newly formed bone with a secondary medullary cavity, depending on the content of monomer next to the tissue. The blood support of the bone came from periosteal vessels. After 6 months a definitive secondary medullary cavity had been established, the cement was enveloped by newly formed primary bone, and the inner and middle portions of the cortical bone had been invaded by vessels originating from the secondary medullary cavity.