{"title":"吲哚美辛对人外周血单核细胞的影响","authors":"E. Razin , B. Klein , A. Globerson","doi":"10.1016/0161-4630(81)90113-0","DOIUrl":null,"url":null,"abstract":"<div><p>Indomethacin treatment (3–8 daily doses of 100 mg) to patients resulted in an increased level of peripheral blood monocytes, as compared to the initial values measured in each individual subject before taking the drug. Normal levels were resumed after the treatment stopped. The idea that these observations were related to the drug treatment per se and not superimposed by the arthritis was verified by the fact that similar results were obtained in healthy volunteers taking this drug.</p></div>","PeriodicalId":76381,"journal":{"name":"Prostaglandins and medicine","volume":"6 5","pages":"Pages 529-536"},"PeriodicalIF":0.0000,"publicationDate":"1981-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0161-4630(81)90113-0","citationCount":"4","resultStr":"{\"title\":\"Effects of indomethacin treatment on human peripheral blood monocytes\",\"authors\":\"E. Razin , B. Klein , A. Globerson\",\"doi\":\"10.1016/0161-4630(81)90113-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Indomethacin treatment (3–8 daily doses of 100 mg) to patients resulted in an increased level of peripheral blood monocytes, as compared to the initial values measured in each individual subject before taking the drug. Normal levels were resumed after the treatment stopped. The idea that these observations were related to the drug treatment per se and not superimposed by the arthritis was verified by the fact that similar results were obtained in healthy volunteers taking this drug.</p></div>\",\"PeriodicalId\":76381,\"journal\":{\"name\":\"Prostaglandins and medicine\",\"volume\":\"6 5\",\"pages\":\"Pages 529-536\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0161-4630(81)90113-0\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Prostaglandins and medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0161463081901130\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Prostaglandins and medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0161463081901130","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of indomethacin treatment on human peripheral blood monocytes
Indomethacin treatment (3–8 daily doses of 100 mg) to patients resulted in an increased level of peripheral blood monocytes, as compared to the initial values measured in each individual subject before taking the drug. Normal levels were resumed after the treatment stopped. The idea that these observations were related to the drug treatment per se and not superimposed by the arthritis was verified by the fact that similar results were obtained in healthy volunteers taking this drug.