[各种截肢神经瘤的组织病理学和超微结构研究]。

A Maleci, G Moretto, F Fenzi, M Poppi, E Govoni, M M Bragaglia, N Rizzuto
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引用次数: 0

摘要

本文介绍了7例截肢神经瘤的光镜和电镜研究结果。神经瘤在肢体外伤性病变的手术中被切除。组织学检查显示神经瘤水平的神经结构完全消失,神经纤维聚集成小束,包裹在异常的神经鞘中,周围是过度生长的结缔组织。在两个病例中发现了远端残端部分和不完全的再神经支配。超微结构检查显示神经纤维异常,包括轴突和轴突与雪旺细胞之间的关系。我们在人身上的数据结果与最近在实验模型中研究的神经再生模式进行了比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Histopathologic and ultrastructural study of various amputation neuromas].

The results of a light and electron microscopy study of seven amputation neuromas are presented. The neuromas were removed during surgery for traumatic lesions of limbs. The histological study showed a complete disappearance of the nerve architecture at the neuroma level, where the fibres are collected in small bundles, enveloped in an abnormal perineural sheath, surrounded by an overgrowing connective tissue. In two cases a partial and incomplete reinnervation of the distal stump was found. The ultrastructural study shows abnormalities of the nervous fibers, both of the axon and of the relationships between the axonal part and the Schwann cell. The results of our data in man are compared to nerve regeneration patterns recently investigated in experimental models.

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