M Casanova, E Kolb, A Vollenweider, F Largiadèr, H G Aberle
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引用次数: 0
摘要
研究脾脏局部照射和免疫抑制药物(环磷酰胺和硫唑嘌呤)对脾内同种异体胰腺移植排斥反应的影响。分式脾照射(移植前4000-5000 rad 1次,移植后500-1000 rad 2次)使移植功能从4.1天延长至6.5天,联合免疫抑制治疗延长至8.5天。
[Delay of early rejection of intrasplenic pancreatic allotransplants by fractional splenic irradiation in dogs (author's transl)].
The influence of local irradiation of the spleen and immunosuppressive drugs (cyclophosphamide and azathioprine) on the rejection of intrasplenic pancreatic allotransplants was studied. Fractional splenic irradiation (once 4000-5000 rad before, twice 500-1000 rad after transplantation) prolonged transplant function from 4,1 to 6,5 days, in combination with immunosuppressive therapy to 8,5 days.