{"title":"花生四烯酸对离体动脉灌注猫眼房水动力学的影响","authors":"G.W.H.M. van Alphen , Frank J. Macri","doi":"10.1016/0161-4630(81)90029-X","DOIUrl":null,"url":null,"abstract":"<div><p>Arterial perfusion of isolated cat eyes with arachidonic acid (AA) increases the inflow of aqueous humor (AH), elevates the intraocular pressure (IOP) and constricts the pupil. The effect may be due to an observed vasoconstrictive action of AA on the blood vessels of the anterior segment of the eye. Indomethacin completely prevents the increase in AH formation and the constriction of the pupil but does not block the rise in IOP.</p></div>","PeriodicalId":76381,"journal":{"name":"Prostaglandins and medicine","volume":"7 5","pages":"Pages 403-409"},"PeriodicalIF":0.0000,"publicationDate":"1981-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0161-4630(81)90029-X","citationCount":"2","resultStr":"{\"title\":\"The effects of arachidonic acid on aqueous humor dynamics of the isolated arterially perfused cat eye\",\"authors\":\"G.W.H.M. van Alphen , Frank J. Macri\",\"doi\":\"10.1016/0161-4630(81)90029-X\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Arterial perfusion of isolated cat eyes with arachidonic acid (AA) increases the inflow of aqueous humor (AH), elevates the intraocular pressure (IOP) and constricts the pupil. The effect may be due to an observed vasoconstrictive action of AA on the blood vessels of the anterior segment of the eye. Indomethacin completely prevents the increase in AH formation and the constriction of the pupil but does not block the rise in IOP.</p></div>\",\"PeriodicalId\":76381,\"journal\":{\"name\":\"Prostaglandins and medicine\",\"volume\":\"7 5\",\"pages\":\"Pages 403-409\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0161-4630(81)90029-X\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Prostaglandins and medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/016146308190029X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Prostaglandins and medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/016146308190029X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The effects of arachidonic acid on aqueous humor dynamics of the isolated arterially perfused cat eye
Arterial perfusion of isolated cat eyes with arachidonic acid (AA) increases the inflow of aqueous humor (AH), elevates the intraocular pressure (IOP) and constricts the pupil. The effect may be due to an observed vasoconstrictive action of AA on the blood vessels of the anterior segment of the eye. Indomethacin completely prevents the increase in AH formation and the constriction of the pupil but does not block the rise in IOP.