肾上腺素对人体NK细胞毒性的增强作用。

Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology Pub Date : 1984-02-01

E Tønnesen, J Tønnesen, N J Christensen

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摘要

8名健康个体皮下注射0.2 mg肾上腺素后，外周血单核细胞NK细胞活性在15-30分钟内升高(p < 0.005)，并在2小时内恢复到基线值。活性与血浆肾上腺素浓度相关(r = 0.52, p < 0.001)。3例对照组注射0.2 ml生理盐水后NK细胞活性无变化。

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Augmentation of cytotoxicity by natural killer (NK) cells after adrenaline administration in man.

After administration of 0.2 mg adrenaline subcutaneously to 8 healthy individuals, natural killer (NK) cell activity of peripheral mononuclear cells increased within 15-30 min (p less than 0.005) and returned to baseline values within two hours. The activity was correlated to plasma adrenaline concentration (r = 0.52, p less than 0.001). No changes in NK cell activity were observed in 3 control subjects receiving an injection of 0.2 ml saline.

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Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology

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