{"title":"一种假定的抗抑郁药，罗利普兰，对一个白天活动的花栗鼠，Eutamias sibiricus的昼夜跑轮活动的影响。","authors":"D Eckhardt, P Reinhard, W Engelmann, B Pflug","doi":"10.1055/s-2007-1017455","DOIUrl":null,"url":null,"abstract":"<p><p>Siberian chipmunks (Eutamias sibiricus) were kept individually in small cages attached to a running wheel. Under continuous illumination of two different light intensities (0.4-0.9 lux and 400-1200 lux) the influence of Rolipram, a putative new antidepressant, on the period length tau was tested. Under both conditions Rolipram caused a lengthening of tau, a decrease of activity time alpha and an increase of rest time delta, resulting in a decrease of the alpha/delta ratio. These effects of Rolipram could be due to a slowing down of the circadian oscillatory system or an influence on the sensitivity towards light.</p>","PeriodicalId":19840,"journal":{"name":"Pharmacopsychiatria","volume":"16 3","pages":"86-9"},"PeriodicalIF":0.0000,"publicationDate":"1983-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2007-1017455","citationCount":"5","resultStr":"{\"title\":\"Effect of a putative antidepressant, Rolipram, on the circadian running wheel activity of a day-active chipmunk, Eutamias sibiricus.\",\"authors\":\"D Eckhardt, P Reinhard, W Engelmann, B Pflug\",\"doi\":\"10.1055/s-2007-1017455\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Siberian chipmunks (Eutamias sibiricus) were kept individually in small cages attached to a running wheel. Under continuous illumination of two different light intensities (0.4-0.9 lux and 400-1200 lux) the influence of Rolipram, a putative new antidepressant, on the period length tau was tested. Under both conditions Rolipram caused a lengthening of tau, a decrease of activity time alpha and an increase of rest time delta, resulting in a decrease of the alpha/delta ratio. These effects of Rolipram could be due to a slowing down of the circadian oscillatory system or an influence on the sensitivity towards light.</p>\",\"PeriodicalId\":19840,\"journal\":{\"name\":\"Pharmacopsychiatria\",\"volume\":\"16 3\",\"pages\":\"86-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1983-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1055/s-2007-1017455\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmacopsychiatria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-2007-1017455\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacopsychiatria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-2007-1017455","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of a putative antidepressant, Rolipram, on the circadian running wheel activity of a day-active chipmunk, Eutamias sibiricus.
Siberian chipmunks (Eutamias sibiricus) were kept individually in small cages attached to a running wheel. Under continuous illumination of two different light intensities (0.4-0.9 lux and 400-1200 lux) the influence of Rolipram, a putative new antidepressant, on the period length tau was tested. Under both conditions Rolipram caused a lengthening of tau, a decrease of activity time alpha and an increase of rest time delta, resulting in a decrease of the alpha/delta ratio. These effects of Rolipram could be due to a slowing down of the circadian oscillatory system or an influence on the sensitivity towards light.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
