{"title":"蛋白质和血小板与聚合物表面的相互作用。","authors":"D R Absolom, W Zingg, C J Van Oss, A W Neumann","doi":"10.3109/10731198409118834","DOIUrl":null,"url":null,"abstract":"<p><p>An attempt is made to develop an understanding of the basic mechanism governing the interaction of the major blood proteins and cells with polymer surfaces with a focus on thermodynamic approach. It is believed that such investigations may be helpful to provide a rational for the design of suitable cardiovascular prosthetic materials and to choose materials in such a way that adsorption of certain proteins eg. 'fibrinogen' is thermodynamically unfavourable compared to adsorption of other proteins eg. 'albumin'.</p>","PeriodicalId":75597,"journal":{"name":"Biomaterials, medical devices, and artificial organs","volume":"12 3-4","pages":"235-66"},"PeriodicalIF":0.0000,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10731198409118834","citationCount":"11","resultStr":"{\"title\":\"Protein and platelet interactions with polymer surfaces.\",\"authors\":\"D R Absolom, W Zingg, C J Van Oss, A W Neumann\",\"doi\":\"10.3109/10731198409118834\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>An attempt is made to develop an understanding of the basic mechanism governing the interaction of the major blood proteins and cells with polymer surfaces with a focus on thermodynamic approach. It is believed that such investigations may be helpful to provide a rational for the design of suitable cardiovascular prosthetic materials and to choose materials in such a way that adsorption of certain proteins eg. 'fibrinogen' is thermodynamically unfavourable compared to adsorption of other proteins eg. 'albumin'.</p>\",\"PeriodicalId\":75597,\"journal\":{\"name\":\"Biomaterials, medical devices, and artificial organs\",\"volume\":\"12 3-4\",\"pages\":\"235-66\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/10731198409118834\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomaterials, medical devices, and artificial organs\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/10731198409118834\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomaterials, medical devices, and artificial organs","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/10731198409118834","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Protein and platelet interactions with polymer surfaces.
An attempt is made to develop an understanding of the basic mechanism governing the interaction of the major blood proteins and cells with polymer surfaces with a focus on thermodynamic approach. It is believed that such investigations may be helpful to provide a rational for the design of suitable cardiovascular prosthetic materials and to choose materials in such a way that adsorption of certain proteins eg. 'fibrinogen' is thermodynamically unfavourable compared to adsorption of other proteins eg. 'albumin'.
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