胎儿血红蛋白降解在极低体重早产儿能量供应中的作用。

J Bókay, M Idei, J Gróf, B Büky, J Menyhárt
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引用次数: 0

摘要

本文对32孕周前出生的低体重早产儿进行了研究,分析其产后血浆血红蛋白下降和氨基酸水平的定量变化。发现早产低体重婴儿的红细胞比成熟新生儿崩解得更快。薄层离子交换色谱研究表明,源自降解血红蛋白f的氨基酸导致血浆氨基酸升高。这些氨基酸可能作为糖异生的底物在低体重早产儿出生后的特殊禁食状态下的能量供应中起作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of degradation of fetal haemoglobin in the energy supply of very low body weight pre-term babies.

Low body weight premature babies born before the 32nd gestational week were studied to analyse the postnatal fall in plasma haemoglobin and in quantitative changes in amino acid levels. Red blood cells of premature low body weight infants were found to disintegrate more rapidly than those of mature newborns. Thin-layer ion-exchange chromatographic studies showed that amino acids originating from the degrading haemoglobin-F lead to rise in plasma amino acids. These amino acids might play a role as substrates for gluconeogenesis in the energy supply of low body weight premature babies during the special fasting state just after birth.

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